Abstract 1176: Pharmacokinetic monitoring of 5-FU appears beneficial in stage II-IV colorectal cancer patients treated with different 5-FU-based chemotherapeutic regimens.
Abstract:The mainstay of colorectal cancer chemotherapy has been 5-fluorouracil (5-FU) alone or in combination with other agents. Unfortunately, therapeutic plasma 5-FU levels are achieved in only 20-30% of patients, in response to administration of 5-FU doses calculated from the patient's body surface area. Pharmacokinetic (PK) monitoring of 5-FU has been found to be beneficial for metastatic colorectal cancer patients. However, its utility among Stage II and III patients has not been reported. Purpose: We examined th… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.