Abstract 11742: Regional Disparities in Major Adverse Cardiac and Cerebrovascular Events During Hospitalizations in Young (18-44 Years) Obese Patients, 2019 National Inpatient Sample Analysis

Abstract

Background: Inpatient outcomes in obese patients have been investigated, although regional inequalities in cardiac and cerebrovascular events in young obese patients have not been explored previously. Methods: The National Inpatient Sample 2019 was queried for young obese patients (18-44 years) in 4 regions (Northeast, Midwest, South, West) using ICD-10-CM codes. Baseline characteristics and comorbidities inpatient MACCE including all-cause mortality, AMI, cardiac arrest, and stroke were identified. Results: Young obese cohort (Total n: 1,285,775, median age: 33 years, females: 75.4%) often consisted of admissions in the South (41.1%), followed by the Midwest (22.3%), West (20.7%), and Northeast (20.7%). HTN and DM were more frequent in the Midwest (32.3% and 22.3%) and South (34.4% and 22.8%) respectively, with higher MACCE of South (3.3%) and Midwest (3%) as compared to Northeast (2.3%) and West (2.6%) regions. All regions had comparable median hospital stay (3 days); however, the admissions in the West and Northeast regions (USD 36861 and 31211) had a higher cost burden. After adjusting for sociodemographic and comorbidities, the odds of in-hospital MACCE were higher in the West (aOR 1.15 95%CI 1.02-1.29), and South (aOR 1.16 95%CI 1.04-1.29), (p<0.001) vs. Northeast admissions (Fig. 1) . Conclusion: Cardiovascular comorbidities and MACCE were higher in young obese admissions in the South. This disparity may be due to differences in behavioral risk factors, socioeconomic status and healthcare access/prices. Future prospective studies on regional differences can help identify high-risk young, obese populations for targeted screening.