Abstract:Introduction:
Recombinant human ACE2 increases the circulating levels of angiotensin-(1-5) [Ang-(1-5)], a peptide thus far regarded as biologically inactive. Since ACE2 is a central component of the protective RAS, we hypothesized that Ang-(1-5) is a new biologically active peptide within this hormonal system.
Objective:
To investigate biological activity and signaling mechanisms of Ang-(1-5).
Methods:
In or… Show more
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