Abstract 10499: The Heart Failure-Induced Long Non-Coding RNA Heat4 Reduces the Inflammatory Response of Non-Classical Monocytes and Mediates Regeneration After Vascular Injury
Abstract:Background and Purpose:
Activation of the immune system correlates with the severity and the prognosis of patients with heart failure (HF). This study aims to identify and characterize long non-coding RNAs (lncRNAs) as a potential mechanistic link between the pathophysiology of HF and the activation of the immune system.
Methods and Results:
Using next-generation sequencing, we identified the lncRNA Heat4 to be 2-fold upregulated in the blood of patient… Show more
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