Abstract:Background:
Abdominal aortic aneurysm (AAA) is recently recognized as an autoimmune-induced vascular disease. Nonetheless, the inflammatory cellular heterogeneity and specialty within the aortic wall have not been fully identified.
Methods:
Infrarenal abdominal aortas of WT mice were perfused with PBS or elastase to simulate sham or AAA models. The aortas were harvested 14 days after surgery and digested for single-cell preparation. The cell pellet was … Show more
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