Absorption of strawberry phytochemicals and antioxidant status changes in humans

Abstract

In this study the antioxidant composition of fresh and stored strawberries and the bioavailability of the main strawberry bioactive compounds were determined in humans. In addition we have investigated plasma total antioxidant capacity. On 13 healthy volunteers, blood samples were collected before and after acute ingestion of fresh and stored strawberries, 300 g respectively. Ferric Reducing Antioxidant Power (FRAP) values after consumption of fresh and stored strawberries showed a significant increase (P < 0.05) at 5 and 8 hours time interval, while significantly decreased TRAP (Total Radical-Trapping Antioxidant Parameter) values (P < 0.05) were found at 8 hours respect to baseline after stored strawberries consumption. After consuming fresh strawberries, plasma levels of ␣-carotene increased significantly (P < 0.05) respect to stored ones. Moreover, consumption of fresh and stored strawberries resulted in a significant increase of vitamin C at 2, 3 and 5 hours (P < 0.05). The bioavailable amount of strawberries antioxidant compounds reflects the variations observed in fresh and stored fruits. We could summarize that the global food quality is related to both native quantity of bioactive compounds and storage treatments.

Strawberry and Achenes Hydroalcoholic Extracts and Their Digested Fractions Efficiently Counteract the AAPH-Induced Oxidative Damage in HepG2 Cells

“…Data describing the polyphenol concentration after in vivo digestion of strawberries are scarce. Azzini et al [ 36 ] described that coumaric acid, protocatechuic acid, and hydroxbenzoic acid were the main compounds quantified in plasma after consuming fresh strawberries, while no traces of quercetin and kampferol were revealed. It is known that the bioavailability of the main phytochemicals of strawberries (anthocyanins) is relatively low (often less than 1% of the ingested dose appears in the plasma or is excreted in the urine) [ 37 , 38 , 39 , 40 , 41 ]; however, its contribution to health effects may be significant.…”

Cultivars, Culture Conditions, and Harvest Time Influence Phenolic and Ascorbic Acid Contents and Antioxidant Capacity of Strawberry (Fragaria x ananassa)

“…The total antioxidant capacity (TAC) results from the presence of several classes of compounds, such ascorbic acid and polyphenolics, which have a different impact on human health (Battino and others 2009). The correlation found between plasma endogenous antioxidant and circulating levels of dietary phenolics underlined the antioxidant action of strawberry phenolic metabolites (Azzini and others 2010) and the benefits of strawberry consumption for human health.…”

Italian Wild Rocket [Diplotaxis Tenuifolia (L.) DC.]: Influence of Agricultural Practices on Antioxidant Molecules and on Cytotoxicity and Antiproliferative Effects

“…Chromatography was performed at 30°C and 1 mL min 1 flow rate using 0.02 M sodium phosphate adjusted with 85% ortophosphoric acid to pH 2.8 (solvent A) and methanol (solvent B). Eluent flow rate was maintained at 1 mL min 1 and the setting potentials were set at 60, 120, 200, 340, 480, 620, 760 and 900 mV [32].…”