Absorption of Orally Administered Emulsified Lipid in Pancreatic Insufficiency in Infants and Children

Lowe, Charles U.; May, Charles D.

doi:10.1111/j.1749-6632.1952.tb30207.x

Cited by 3 publications

(1 citation statement)

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“…A few, however, think that the value of pancreatic preparations is doubtful owing to variations in their potency, to the relatively slight improvement of absorption, and decreased appetite (13,16,19).…”

Section: Introductionmentioning

confidence: 99%

On the Effectiveness of Our Pancreatic Enzyme Preparations A Study of Fat and Protein Absorption and of the Total Amount of Faeces

Jensen¹,

Schneidelbach²

1956

Acta Paediatrica

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Summary The effectivity of various pancreatic enzyme preparations was tested on a boy, aged 2 3/4 years, with congenital cystic fibrosis of the pancreas. These preparations were Pancreatin RMC, Pancreon tablets (Rhenania), and Zymopan tablets (MCO). During periods with no treatment the absorption of fat and protein was 52–64 % and 40–49 % respectively, and the stools were trypsin negative. During treatment with Pancreatin RMC the fat and protein absorption was 80–86 % and 71–86 % respectively, and the stools were trypsin positive. During treatment with Pancreon the fat and protein absorption was 70–84 % and 64–74 % respectively, and the stools were trypsin positive. During treatment with Zymopan the corresponding values were 60–65 % and 49–63 %, and the stools were trypsin negative. Sur l'activité de nos préparations d'enzymes pancréatiques. Comparaison entre trois préparations d'enzymes pancréatiques: l'étude montre que la Pancréatine RMC est une préparation extrêmement active pour le traitement de la fibrose pancréatique de l'enfant. Le Pancréon a un effet certain, mais un peu moins marqué, tandis que le Zymopan est pratiquement inactif, comme Fa aussi prouvé l'étude de Bastrup‐Madsen et Mortensen. Über die Wirksamkeit unserer Pancreasenzympräparate. Drei Pancreasfermentpräparate sind verglichen worden. Es wurde gezeigt, dass Pancreatin RMC ein hochst wirksames Präparat in der Behandlung von Pancreasfibrose bei Kindern ist. Pancreon hat einen guten, aber einen etwas weniger deutlichen Effekt, während Zymopan praktiseh unwirksam ist, wie auch durch die Untersuchung von Bastrup‐Madsen und Mortensen gezeigt wurde. Sobre la efectividad de nuestros preparados de enzima pancreática. Tres preparados de enzima pancreática fueron comparados. El pancreatín RMC es de gran efectividad en el tratamiento de la fibrosis pancreática en la infancia. El Pancreon tiene un buen efecto aunque menor que el anterior mientras el Zymopan es prac‐ticamente inefectivo, dato corroborado por los estudios de Bastrup‐Madsen y Mortensen.

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Section: Introductionmentioning

confidence: 99%