Dust is an important component of the interstellar medium of galaxies. Dust dominates the extinction, hence also radiative transfer, of non-ionizing radiation and therefore the optical to sub-millimeter appearance of galaxies. The high dust extinction for energetic UV photons -associated with molecular cloudsalso allows molecules to survive. Moreover, grain surfaces provide a catalytic agent for the drive towards molecular complexity in these environments. Small grains also play a major role in the energy balance of interstellar gas through the photoelectric effect, so they control the phase structure of the interstellar medium. Eventually, these small dust grains partake in the process of star and planet formation. In particular, this dust coagulates into larger "dust balls" and eventually cometesimals and planetesimals in the disks around young stellar objects in the first steps towards the formation of a new planetary system. It is clear that many of the key processes in the interstellar medium involve dust and, conversely, that the characteristics and physical properties of dust are key to our understanding of the Universe.The presence of interstellar dust grains was first surmised from their extinction effects on starlight (Trumpler 1930), and for much of the last century most of our information on interstellar dust was derived from extinction studies supplemented by a smither of scattering and polarization data. Really what this data probed was the size distribution of interstellar dust and during the sixties and seventies -thanks to the opening up of the UV window by space-based observations -these studies culminated in the influential Mathis et al. (1977) dust model with steep (index -3.5) powerlaw grain size distributions ranging from 100 Å to 3000 Å. The field sort of stagnated at this point. Admittedly, at about any astronomical meeting in the next decade, there was much discussion on the composition, origin, and evolution of interstellar dust -aspects that were not wellconstrained by the observations -but that was mainly driven by the force of personalities rather than by new developments.In hindsight, this started to change dramatically in the late seventies, driven by the advent of infrared detector technology, which in many ways provided a new view of the dusty Universe. Some of this reflected the rise of infrared absorption spectroscopy as a very powerful way of probing the composition of solid compounds. Studies of infrared emission spectra, though, provided a much more dramatic revolution in our understanding of interstellar dust. In particular, airborne observations revealed that broad emission features dominate the mid-infrared spectra of many luminous objects. Subsequently, observations with the InfraRed Astronomical Satellite showed that widespread mid-infrared emission is a general characteristic of the diffuse interstellar medium. In a seminal paper in the mideighties, Kris Sellgren (1984) observed mid-infrared emission far from the illuminating stars in reflection nebulae and realized th...