Absorption of Fat and Calcium by Infants Fed a Milk-Based Formula Containing Palm Olein

Nelson, Steven E.; Frantz, Joan A.; Ziegler, Ekhard E.

doi:10.1080/07315724.1998.10718770

Cited by 69 publications

(85 citation statements)

References 15 publications

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“…Although it is generally stated that calcium bioavailability is lower from infant formulas than from human milk, this may not always be the case (Fomon & Nelson, 1993;Institute of Medicine, 1997). In general, however, values of 30-40% absorption are typical for cow milk-based infant formulas or whole cow milk (Nelson, Frantz, & Ziegler, 1998). The efficiency of calcium absorption from any food source is likely to depend more on the total amount added and its interaction with other food components (Heaney, Recker, & Weaver, 1990).…”

Section: Bioavailability Of Calcium From Calcium-fortified Milkmentioning

confidence: 99%

Heat stability and calcium bioavailability of calcium-fortified milk

Singh

Arora

Sharma

et al. 2007

LWT - Food Science and Technology

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Section: Bioavailability Of Calcium From Calcium-fortified Milkmentioning

confidence: 99%

Heat stability and calcium bioavailability of calcium-fortified milk

Singh

Arora

Sharma

et al. 2007

LWT - Food Science and Technology

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“…Formulas containing palm oil or palm olein oil as fat sources have been shown to result in reduced Ca absorption [2][3][4] and reduced bone mineral content (BMC) and bone mineral density (BMD) [5]. Additionally, unabsorbed fatty acids combine with unabsorbed Ca forming Ca-fatty acid soaps which result in firmer stools [6].…”

Section: Introductionmentioning

confidence: 99%

Tolerance, Bone Mineral Content, and Serum Vitamin D Concentration of Term Infants Fed Partially Hydrolyzed Whey-based Infant Formula

Borschel¹

2012

TONUTRJ

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Abstract:The objective of the study was to assess the tolerance (intake, incidence of spit up/vomit, and stool patterns), bone mineral status, and vitamin D status of healthy, term infants fed one of two partially hydrolyzed bovine whey protein infant formulas from birth to 56 or 84 days of age. The control formula was commercially available and was compared to an experimental formula.Eighty-nine term infants were enrolled in the study and 74 (83%) completed the study. The control formula had similar vitamin D but lower calcium and phosphorus content and contained palm olein oil and lactose compared to the experimental formula. Infants fed the experimental formula exhibited significantly greater serum 25-OH vitamin D levels at 2 months of age, significantly greater bone mineral content as assessed by dual-energy x-ray absorptiometry at 3 months of age and softer stools during the study period compared to infants fed the control formula. No differences were observed between groups for formula intake, incidence of spit up/vomit, anthropometric measurements, or serum concentrations of calcium, phosphorus, skeletal alkaline phosphatase, or parathyroid hormone.The results suggest that both study formulas are safe but differ in the metabolic response of infants fed the formula. Bone mineral content in these infants reflected differences in levels of nutrients important to calcium between two formulas over the short-term. Long-term implications and clinical relevance of these findings are unknown and require further study. These results provide additional knowledge regarding the typical vitamin D status as assessed by serum 25-OH vitamin D of healthy term formula-fed infants.

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“…Além de seu baixo teor em cálcio, a dieta de cafeteria é rica em gordura, que pode interferir na absorção desse íon pelo intestino, diminuindo a biodisponibilidade do mesmo para gênese óssea, como já demonstrando em estudos anteriores (NELSON;FRANTZ;ZIEGLER, 1998). Considerando a importância do cálcio em diversas funções orgânicas, aliado ao fato deste não ser sintetizado endogenamente e estar depositado principalmente no tecido ósseo (99%) (MAHAN; ESCOTT--STUMP, 2010), a ingestão inadequada de cálcio culmina com a mobilização da forma mineral desse íon a partir dos fluidos ósseos, ou diretamente por meio da atividade osteoclástica (MAHAN; ESCOTT-STUMP, 2010), culminando com o aumento da reabsorção óssea.…”

Section: Discussionunclassified

Obesidade materna associada ao tratamento com Losartan: efeitos sobre o esqueleto da prole de ratas

Kunz¹,

Reis²,

Santos³

et al. 2017

cmbio

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ResumoIntrodução: a obesidade, uma pandemia mundial, é uma condição clínica que se relaciona com diversas comorbidades, como a hipertensão arterial, que pode ser farmacologicamente tratada com Losartan. A complexidade da obesidade associada ao uso de medicamentos poderia programar metabolicamente diversos sistemas orgânicos, como o tecido ósseo. Objetivo: verificar os potenciais efeitos da obesidade associada ao uso de Losartan como programador metabólico sobre parâmetros histomorfométricos do tecido ósseo da prole. Metodologia: Foram utilizadas ratas Wistar, divididas em grupos controle (CTL), que recebeu ração padrão e água; e tratado (CAF+ LOS), que recebeu dieta de cafeteria ad libitum e Losartan diariamente por meio de gavagem. Aos 70 dias de vida as ratas foram submetidas ao cruzamento com machos da mesma espécie. A partir dos 21 dias de vida, a prole foi alimentada com ração padrão até os 100 dias de vida, quando 8 fêmeas de cada grupo foram pesadas e eutanasiadas. Foram coletadas e pesadas as gorduras retroperitoneal e perigonadal. Em seguida, as tíbias direitas foram coletadas e submetidas ao processamento histológico de rotina para microscopia de luz, com posterior análise de parâmetros histomorfométricos. Resultados: houve um aumento estatisticamente significativo no acúmulo de gordura perigonadal nas ratas do grupo CAF+LOS, bem como menor área do canal medular da tíbia nestas ratas em relação ao grupo CTL. Conclusão: a obesidade induzida por dieta de cafeteria associada ao uso de Losartan programou a prole por meio do aumento no acúmulo de gordura perigonadal e redução da área do canal medular da tíbia. Palavras-chave: Tecido Adiposo. Hipertensão. Tíbia. Abstract Introduction: obesity, a global pandemic, is a clinical condition that is associated with several co-morbidities such as hypertension

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Absorption of Fat and Calcium by Infants Fed a Milk-Based Formula Containing Palm Olein

Abstract: Absorption of fat and calcium by normal infants is lower when palm olein provides a substantial proportion of formula fat than when formula does not contain palm olein.

Cited by 69 publications

References 15 publications

Heat stability and calcium bioavailability of calcium-fortified milk

Heat stability and calcium bioavailability of calcium-fortified milk

Tolerance, Bone Mineral Content, and Serum Vitamin D Concentration of Term Infants Fed Partially Hydrolyzed Whey-based Infant Formula

Obesidade materna associada ao tratamento com Losartan: efeitos sobre o esqueleto da prole de ratas

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