Absorption of Colostral Immunoglobulins in Newborn Calves

Bush, L.J.; Staley, T. E.

doi:10.3168/jds.s0022-0302(80)82989-4

Cited by 167 publications

(140 citation statements)

References 58 publications

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“…Calves are born with almost no circulating immunoglobulin (Ig) [27]. Calves are dependent on Ig absorbed from colostrum [6], however, the maternal antibody is catabolized at 3 weeks of age [2]. Antibody to different bacterial, protozoal and viral antigens was not produced or did not appear until 2 to 4 weeks of age [13,15,26].…”

Section: Methodsmentioning

confidence: 99%

Relationship between Age-Dependent Changes Of Bovine Neutrophil Functions and Their Intracellular Ca2+ Concentrations.

Higuchi

Nagahata

Hiroki

et al. 1997

The Journal of Veterinary Medical Science

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ABSTRACT. Neutrophil functions and intracellular Ca 2+ concentrations ([Ca 2+ ]i) were evaluated in 15 Holstein cattle divided into the following 3 groups: 5 neonatal calves less than 1 week old (group 1), 5 young calves 2 to 4 weeks old (group 2) and 5 cows 2 to 3 years old (group 3). The ability of neutrophils to phagocytose Candida albicans (C. albicans) was significantly higher (p<0.05) in neonatal and young calves than in cows, whereas the phagocytosis by neutrophils of bovine IgG-coated yeasts (IgG-yeasts) was significantly lower (p<0.05) in neonatal and young calves than that in cows. The killing activity by neutrophils of C. albicans in neonatal and young calves was significantly lower (p<0.05) than that in cows. Luminol dependent chemiluminescent (LDCL) responses stimulated with opsonized zymosan (OPZ), heat-aggregated IgG (H-agg.IgG) and phorbol myristate acetate (PMA) were apparently lower in neonatal and young calves than in cows. No clearly different expressions of complement receptor type 3 (CR3) on neutrophils were observed among the 3 groups of cattle, although the values due to the binding of FITC-anti-bovine IgG to neutrophils in neonatal and young calves were lower than those in group 3. The OPZ-induced [Ca 2+ ]i of neutrophils in neonatal and young calves were significantly higher (p<0.05) than those in cows, but they were lower in neonatal and young calves when stimulated with H-agg.IgG. These results indicate that CR3-and FcRmediated phagocytic and killing activities of neutrophils in neonatal and young calves are different from those in cows. These phenomena may be associated with age-dependent changes in [Ca 2+ ]i. -KEY WORDS: intracellular Ca 2+ concentration, neonatal calf, neutrophil function, young calf.

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Section: Methodsmentioning

confidence: 99%

Relationship between Age-Dependent Changes Of Bovine Neutrophil Functions and Their Intracellular Ca2+ Concentrations.

Higuchi

Nagahata

Hiroki

et al. 1997

The Journal of Veterinary Medical Science

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“…En effet, la détermination des activités des principales enzymes protéolytiques du tractus digestif a montré que ce potentiel hydrolytique est relativement faible à cet âge ; seule l'activité de la chymosine abomasale, qui provoque la coagulation de la caséine du colostrum, est élevée, chez le veau comme chez l'agneau, alors que celle des principales protéases pancréatiques (chymotrypsine, trypsine) est basse (Guilloteau et al, 1985). De plus, l'intestin grêle présente une perméabilité temporaire (24 h environ) qui permet l'absorption de protéines alimentaires intactes (Bush et Staley, 1980 ;Levieux, 1984 (Bourdel et al, 1981), porc (Rérat, 1985), mouton (Bergman et Heitman, 1980), chèvre (Greppi et Champredon, 1985 …”

Section: Introductionunclassified

Digestion des protéines de lait et métabolisme de la méthionine chez l'agneau nouveau-né

Patureau-Mirand¹,

Champredon²,

Prugnaud³

et al. 1987

Reprod. Nutr. Dévelop.

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Summary. Protein digestion and methionine metabolism in newborn lambs.Methionine absorption and catabolism were studied in 4 newborn lambs during the first 8 h after birth. Lambs were hourly fed 50 ml goat milk labelled with 35 S-methionine and 35 S_cysteine. The free amino acid levels and the specific activity of free methionine were measured in jugular blood samples collected 1 h (just before the first meal), 4, 6 and 8 h after birth and in the portal blood 8 h after birth. Specific activities of protein-bound methionine and cysteine were measured in the milk and then in the abomasal and intestinal contents as well as in the liver, intestine and whole body proteins, 8 h after birth.The jugular blood levels of free valine, isoleucine, leucine, phenylalanine and histidine increased significantly between 1 and 8 h whereas the levels of free alanine, serine, glycine, citrulline and 3-methylhistidine decreased. The concentrations of most free amino acids were 30 % higher in portal than in jugular blood. In the abomasal contents, the specific activities of methionine and cysteine were 96 and 168 %, respectively of that of ingested milk and in the intestinal contents the corresponding values were 24 and 31 % (table 11. In the jugular blood, the specific activity of methionine reached a plateau before 5 h after the first meal ; in the portal blood 8 h after birth it represented 75 % of the specific activity entering the small intestine. The blood methionine flux was calculated according to two methods : 1) from whole-body protein synthesis rates and methionine catabolism and 2) from the irreversible loss of blood methionine (table 2). Comparison of these estimates shows that in newborn lambs fed on goat milk, nearly all methionine entering the intestine may be available at the peripheral blood level. However, a portion of the absorbed labelled methionine did not seem to appear in the portal blood as free methionine. Methionine catabolism differed widely between the four lambs (table 2) and this variation was related to that of the specific activity of cysteine in the liver proteins ( fig. 11. ).Introduction.

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“…Le colostrum fournit les nutriments nécessaires à la survie et au développe-ment du nouveau-né au cours de ses premières heures ; il se caractérise, en particulier, par sa richesse en protéines (immunoglobulines principalement) dont la digestion, plus ou moins partielle chez les ruminants, alimente l'organisme en protéines intactes ou peu dégradées (Bush et Staley, 1980) et en acides aminés. Le lactose du colostrum est aussi une source de glucose pour le nouveau-né.…”

Section: Introductionunclassified

Métabolisme protéique de l'agneau nouveau-né. — I. Conséquences de l'ingestion de colostrum sur la glycémie, la gammaglobulinémie et les teneurs en acides aminés libres des tissus

Patureau-Mirand¹,

Bernard²,

Prugnaud³

et al. 1985

Reprod. Nutr. Dévelop.

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Absorption of Colostral Immunoglobulins in Newborn Calves

Cited by 167 publications

References 58 publications

Relationship between Age-Dependent Changes Of Bovine Neutrophil Functions and Their Intracellular Ca2+ Concentrations.

Relationship between Age-Dependent Changes Of Bovine Neutrophil Functions and Their Intracellular Ca2+ Concentrations.

Digestion des protéines de lait et métabolisme de la méthionine chez l'agneau nouveau-né

Métabolisme protéique de l'agneau nouveau-né. — I. Conséquences de l'ingestion de colostrum sur la glycémie, la gammaglobulinémie et les teneurs en acides aminés libres des tissus

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