Absorption and Oxidation of Medium-chain Triglyceride Infused into Rat Thiry-Vella loops.

Abstract

Absorption and oxidation of medium-chain triglyceride (MCT) and long-chain triglyceride (LCT) infused in vivo into intestinal loops (Thiry-Vella loop) were studied. Thiry-Vella loops were formed in rat peritoneum using 20cm of jejunum resected from the same animal, both ends being attached open at the peritoneal wall. Thus each prepared loop was used as an in vivo intestine system free from bile and pancreatic juice. Normal absorbability in each loop was confirmed by infusion of a [14C]glucose. Three hours' cumulative absorption of [14C]MCT and [14C] LCT infused into the loop was assayed. The absorption rate of [14C] MCT was significantly higher than that of [14C] LCT, being Key Words medium-chain triglyceride, long-chain triglyceride, Thiry-Vella loop, energy metabolism, absorption.