Absorption and metabolism of [14C]allethrin by the adult housefly, Musca domestica L.

Oxidative metabolism of pyrethroids in houseflies

“…and synthetic pyrethroids are relatively harmless to mammals but are extremely toxic to houseflies, mosquitoes, and many other insect pests, especially in the presence of synergists. Despite these favorable properties, early attempts to elucidate their penetration characteristics and metabolic fate in houseflies (Bridges, 1957;…”

Mechanisms of Resistance Against Insecticides

“…A similar absence of chrysanthemum acids was reported by Hopkins & Robbins (99) for the excreta from house flies treated with allethrin, which contained a substance resembling allethrolone; although nearly half of the dose was excreted in the first day, no unchanged allethrin was present. Bridges (29) found that allethrin was rapidly absorbed and metabolized by normal house flies, the detoxication being faster in the abdomen than in the thorax and in females than in males. However, lipase preparations even from female abdo mens were relatively inactive in detoxifying allethrin and were unaffected by piperonylcyclonene; it was concluded that hydrolysis plays a small part, if any, in the breakdown of allethrin.…”

DOSE DEPENDENCE OF THE RATE OF PENETRATION OF TOPICALLY APPLIED DDT-C14 INTO THE HOUSE FLY

“…They also stated that the data of Matsumura (1963) and Sternberg et al (1950) were found to conform with this hypothesis, though from their paper it is not clear whether the data of Sternberg et al (1950) or Vinson and Kearns (1952) were analyzed. Bridges (1957) found the reverse to be true in the case of house flies when allethrin-C'" was applied topically. In support of her hypothesis she has also used the data of Sternberg et al (1950).…”