Absolute Stereochemistry of TXIB, a Bioactive Plasticizer That Inhibits Oviposition of the Peach Fruit Moth, Carposina sasakii (Lepidoptera: Carposinidae)

Tribute to Professor Kenji Mori and his contribution to Chemical Ecology

“…How Professor Mori would have enjoyed the challenge of synthesizing all eight stereoisomers! Kazama et al (2022) describe investigations of the stereochemistry of a synthetic plasticizer which was previously shown to inhibit oviposition in the peach fruit moth, Carposina sasakii. Only the (R)-enantiomer elicited an EAG response and inhibited oviposition, a remarkable example of how stereochemistry influences the biological activity even of entirely non-natural compounds.…”