Absolute increase in tumour size can improve the metric evaluating disease progression in metastatic colorectal cancer
Ari Robinson,
Zvia Agur,
Yuri Kogan
Abstract:Background
The assessment of response to therapy in advanced solid cancer diseases is predicated on the Response Evaluation Criteria In Solid Tumours for the evaluation of disease state by the relative changes in lesion size. The underlying assumption is that a larger relative increase in lesion size implicates less efficacious therapy, worse prognosis and shorter survival.
Methods
We analyzed retrospective data of metastatic colorectal cancer patients from three clinical datasets, stratified into three coho… Show more
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