Absolute flow measurement in chicken embryo based on optical coherence tomography with direct Doppler angle measuring

Ma, Yushu; Zhao, Yuqian; Jiang, Huiwen; Yang, Lin; Li, Ang; Meng, Ziyue; Liu, Jian; Yu, Yao; Wang, Yi; He, Zuyuan; Shi, Wenbo; Ma, Zhenhe

doi:10.1016/j.infrared.2022.104053

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2023

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“…Increasing the Doppler angle can alleviate the issue of phase wrapping to some extent (Equation ( 3)). However, it should be noted that the accuracy of the velocity measurement deteriorates when the Doppler angle approaches π/2 [37]. Generally, blood flow in vessels exhibits quasi-laminar flow, i.e., where the flow velocity gradually increases from the border to the center.…”

Section: Discussionmentioning

confidence: 99%

The Stress Phase Angle Measurement Using Spectral Domain Optical Coherence Tomography

Zhao,

Zhu,

Jiang

et al. 2023

Sensors

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The stress phase angle (SPA), defined as the temporal phase angle between circumferential stress (CS) in the arterial wall and wall shear stress (WSS), is utilized to investigate the interactions between CS and WSS. SPA serves as an important parameter for the early diagnosis of cardiovascular disease. In this study, we proposed a novel method for measuring SPA using spectral domain optical coherence tomography (SD-OCT). The multi-M-mode scan strategy is adopted for interference spectrum acquisition. The phases of CS and WSS are extracted from the corresponding structural and flow velocity images of SD-OCT. The method is validated by measuring SPA in the outflow tract (OFT) of chick embryonic hearts and the common carotid artery of mice. To the best of our knowledge, this is the first time that OCT has been used for SPA measurement.

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Section: Discussionmentioning

confidence: 99%