Absence of SARS-CoV-2 in Semen of a COVID-19 Patient Cohort

Guo, Liqiang; Yuan, Mingzhen; Li, Weiguang; Wang, Yong; Li, Leping; Jiang, Shujuan; Ren, Wei; Yan, Qun; Zhang, Fubin; Kong, Feng; Lei, Jie; Zhao, Shengtian

doi:10.2139/ssrn.3615915

Cited by 37 publications

(49 citation statements)

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“…Our study argues that there is probably no additional transmission risk via semen. The available data also support our study that SARS-CoV-2 is not a sexually transmitted virus [ 4 , 5 , 6 , 7 , 8 ]. However, sexual contact carries a high risk in terms of SARS-CoV-2 transmission between partners through the respiratory secretions, not semen.…”

supporting

confidence: 85%

Semen Does Not Cause Additional Risk for SARS-CoV-2 Transmission during Sexual Contact

Kayaaslan

Korukluoğlu²,

Hasanoğlu

et al. 2020

Urol Int

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supporting

confidence: 85%

Semen Does Not Cause Additional Risk for SARS-CoV-2 Transmission during Sexual Contact

Kayaaslan

Korukluoğlu²,

Hasanoğlu

et al. 2020

Urol Int

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“…Sexual transmission of SARS-CoV-2 has been under investigation from the early time of the pandemic, and the presence/absence of SARS-CoV-2 in semen has been studied in case series. However, the findings of these studies have revealed conflicting results [ 4 , 5 , 6 , 17 , 18 , 19 ]. In fact, most of the studies investigating SARS-CoV-2 in semen reported that the virus could not be detected in semen [ 5 , 17 , 18 , 19 ].…”

Section: Discussionmentioning

confidence: 99%

“…However, the findings of these studies have revealed conflicting results [ 4 , 5 , 6 , 17 , 18 , 19 ]. In fact, most of the studies investigating SARS-CoV-2 in semen reported that the virus could not be detected in semen [ 5 , 17 , 18 , 19 ]. First, it was reported that SARS-COV-2 was not detected in semen of a 31-year-old man in the recovery period [ 4 ].…”

Section: Discussionmentioning

confidence: 99%

Investigation of SARS-CoV-2 in Semen of Patients in the Acute Stage of COVID-19 Infection

Kayaaslan

Korukluoğlu²,

Hasanoğlu

et al. 2020

Urol Int

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Introduction: The presence of new coronavirus (SARS-CoV-2) in semen and the possibility of sexual transmission have become new subjects of curiosity. There is a discrepancy regarding this issue in the literature. The presence of SARS-CoV-2 in semen has been investigated in a limited number of studies, and mostly in recovering patients. We aimed to investigate the presence of SARS-CoV-2 RNA in semen of patients with a positive nasopharyngeal swab test for SARS-CoV-2 in the acute stage. Methods: We enrolled adult male patients who were hospitalized with confirmed SARS-COV-2 infection in the study. In addition to routine laboratory and radiological tests, semen sample was obtained from volunteers and transferred to the Turkish Public Health Institution, National Virology Laboratory. The samples were processed for the detection of SARS-CoV-2 RNA on the day of collection. Results: Sixteen patients were included in the study. The median age was 33.5 years (18-54). All but one had respiratory symptoms. None of the patients had a history or symptoms of urogenital disease. All semen samples were obtained during hospitalization and in the acute stage of the infection. The median time to obtain a semen sample after positive nasopharyngeal test was 1 day (0-7). All semen samples were detected as negative for SARS-CoV-2 PCR. Discussion/Conclusion: Although all semen samples were obtained in acute stage of the infection when the nasopharyngeal swab test was positive, we did not detect SARS-CoV-2 in semen. The results of our study support the thought that sexual transmission via semen does not have an important role in the person-to-person transmission of SARS-CoV-2. We think that our study will provide new information to fill the gap in the literature.

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“…There is evidence that the main entry receptor of SARS-CoV-2, ACE2, is expressed in cells of the reproductive system [ 153 , 154 ]. However, one study with 23 COVID-19 patients in the acute (12 patients) and recovery phase (11 patients) failed to detect viral RNA in semen [ 155 ], indicating a low probability of sexual transmission through semen.…”

Section: Introductionmentioning

confidence: 99%

Potential sources, modes of transmission and effectiveness of prevention measures against SARS-CoV-2

Kampf

Brüggemann

Kaba

et al. 2020

Journal of Hospital Infection

127

121

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Absence of SARS-CoV-2 in Semen of a COVID-19 Patient Cohort

Cited by 37 publications

References 0 publications

Semen Does Not Cause Additional Risk for SARS-CoV-2 Transmission during Sexual Contact

Semen Does Not Cause Additional Risk for SARS-CoV-2 Transmission during Sexual Contact

Investigation of SARS-CoV-2 in Semen of Patients in the Acute Stage of COVID-19 Infection

Potential sources, modes of transmission and effectiveness of prevention measures against SARS-CoV-2

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