Absence of a Pedicle in the Spine Metastatic Disease Versus Aplasia

Ge, Degesys; Miller, G. A.; Ge, Newman; Cohan, Richard H.

doi:10.1097/00007632-198601000-00023

Cited by 2 publications

(1 citation statement)

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“…There have also been cases with erosion from metastases resembling aplasia of the pedicles. 23 Hemangiomas have also been described with osseous destruction. In a series of seven cases, Gao et al report the presence of an epidural extension of spinal hemangiomas.…”

Section: Discussionmentioning

confidence: 99%

Undifferentiated presentation of unilateral agenesis of a cervical pedicle and a contiguous vertebral hemangioma: illustrative case

Alsuwaihel

El-Mughayyar

MacLennan

et al. 2022

Journal of Neurosurgery: Case Lessons

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BACKGROUND Unilateral agenesis of a cervical pedicle is a known rare entity that has been well described over the past 70 years. It is usually an incidental or minimally symptomatic presentation with no significant clinical repercussion. No previous report has described concurrent non-osseous developmental abnormalities alongside this unique pathology. OBSERVATIONS This case reported a cervical hemangioma with associated unilateral pedicle agenesis and an incidental finding of callosal dysgenesis and lipoma. The initial presentation consisted solely of persistent neck pain, with cervical radiography illustrating significant kyphotic deformity secondary to apparent anterolisthesis of C3-C4. The patient underwent a combined approach: anterior cervical corpectomy at C4-C5 with supplemental posterior fusion. The authors provided a review of the literature concerning developmental pedicle abnormalities and vertebral hemangioma. Pedicle agenesis is known to be associated with multiple pathologies, but the authors have not found evidence of a clinical paradigm consisting of a vertebral hemangioma in the presence of cervical pedicle agenesis, callosal dysgenesis, or callosal lipoma. LESSONS Careful evaluation of radiographs with appropriate subsequent multimodal imaging is key to identifying unique pathologies in the spine that complement a patient’s history and clinical findings. If multiple abnormalities are noted, a novel clinical etiology or syndrome must be considered.

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Section: Discussionmentioning

confidence: 99%