Abscisic Acid in Treating Neurodegenerative and Other Diseases- An Overview

Abstract

Neurodegenerative diseases arise when neurons in the brain or the peripheral nervous system gradually lose function and die. Millions of people globally are affected by neurodegenerative diseases. With age, the chance of getting a neurodegenerative disease increases dramatically. Many of your body's functions are affected by degenerative nerve diseases, including balance, motion, speaking, respiration, and heart function. Alzheimer's disease (AD) is among the most prevalent type of dementia in the elderly. Abscisic acid (ABA) is a plant hormone found in fruits and vegetables that can be obtained naturally through diet and has previously been investigated for its potential health benefits. It has antioxidant and anti-inflammatory effects, and it improves cognitive learning and memory function. ABA has been shown to play an important part in the metabolism of glucose, inflammation, memory, and tumor growth. This review focuses on ABA's novel and promising role as a possible treatment for a variety of neurodegenerative disorders such as Alzheimer's and ADHD. We also included studies on illnesses such as diabetes mellitus and murine allergic airway inflammation. All of the studies referred to in this review demonstrate that ABA is effective in treating these diseases.

Huperzine a Extraction From Huperzia Serrata and Its Mechanism of Treating Alzheimer's Disease: A Review

“…cholinergic signalling that enhances the expression of neurotrophic factors, synaptic activity, antagonistic activity of the N-methyl-D-aspartate (NMDA) receptor (NMDAR), control of ROS, and neuronal survival is what causes HupA therapy to have neuroprotective benefits (14,52). One of the neuroprotective mechanisms of HupA is synaptic vesicle release.…”