Abrasive immobilization of carbon nanotubes on a basal plane pyrolytic graphite electrode: application to the detection of epinephrine

Abstract

The performance of a basal plane pyrolytic graphite (bppg) electrode modified with carbon nanotubes is described. Abrasive immobilization of multiwall carbon nanotubes on a bppg electrode was achieved by gently rubbing the electrode surface on a filter paper supporting carbon nanotubes. The resulting electrode showed excellent mediation of epinephrine oxidation: a decrease in the overvoltage of the epinephrine electro-oxidation (200-500 mV) was observed as well as a dramatic increase in the peak current (4 times) compared to that seen at a bare bppg electrode. The oxidation peaks of epinephrine and ascorbic acid which overlap on bare bppg electrode were separated successfully (by ca. 220 mV) at the surface of the modified bppg electrode. The modified electrode showed good stability in comparison to most modified carbon nanotubes electrodes prepared by alternative methods.

Electrocatalytic properties of prussian blue nanoparticles supported on poly(m-aminobenzenesulphonic acid)-functionalised single-walled carbon nanotubes towards the detection of dopamine

“…They are essential and promising materials in the field of nano-science and nanotechnology because of their electronic properties and large surface area [1][2][3]. Their contribution to the improvement of electrical properties of some bare electrode such as the glassy carbon [4][5][6], graphite [7][8][9][10], carbon fiber [11], gold [12][13][14][15], and platinum (Pt) electrodes [16] have been reported. As part of its numerous applications, Han et al [17] considered CNTs as suitable mediators for prussian blue (PB)-modified electrodes because of their good electrical conductivity and the property of being particle carriers.…”

Electrochemical properties of surface-confined films of single-walled carbon nanotubes functionalised with cobalt(II)tetra-aminophthalocyanine: Electrocatalysis of sulfhydryl degradation products of V-type nerve agents

“…Adhesion of CNT onto GCE is difficult and fraught with problems such as irreproducibility [19], therefore the use of basal plane pyrolytic graphite (BPPGE) or edge plane pyrolytic graphite (EPPG) are preferred because of the inherent ability of these electrodes to interact with CNTs via π-π interactions [20], [21] and [22]. As part of our on-going investigations geared towards harnessing the twin properties of electroactive amino-substituted transition MPc (notably, the CoTAPc) complexes and CNTs [23] and [24], this work is aimed at investigating the electrochemical and The serious threats posed to the society by terrorists have made the fast detection of organophosphates based chemical warfare agents (CWAs), especially those of the V-type nerve agents and their sulfhydryl hydrolysis products [25] and [26] (Table 1) a major global concern.…”

Electrochemical sensors based on carbon nanotubes and their use in biomedical research

“…Было установлено, что в отличие от немодифицированного графитового электрода сенсор характеризовался снижением электрического потенциала окисления этого химического соединения (200-500 мВ), а также увеличением сигнала в четыре раза. Более того, сигналы, соответствовавшие процессам окисления адреналина и аскорбиновой кислоты и перекрывавшиеся при использовании немодифицированного графитового электрода, при применении данного сенсора наблюдались при электрических потенциалах, различавшихся на 220 мВ [31].…”

“…гомоцистеин [67], глутатион [34,46], дисульфид глутатиона [46], адреналин [31,32,45], норадреналин [32], морфин [33], тиоцитозин [34], холестерин [37], гидрохинон [44], пирокатехин [44,49], резорцин [44], тирозин [60], дофамин [45,59,63,64], серотонин [59], ацетилхолин [48], хлорфенол [49], амино- [65] и нитрофенолы [68], крезол [49], ксантин [39], гетероауксин [51], тироксин [52], азитромицин [53], метронидазол [54], танин [55], резерпин [56], митоцин [57], симвастин [58], каталазу [42], мочевину [48], NADH [32], углеводы [35,62,66,69,71,72] и многие другие химические соединения. Более того, при помощи этих сенсоров можно анализировать ДНК(по результатам определения гуанина и аденина [61].…”

“…Применение углеродных нанотрубок в электрохимических сенсорах приводит к существенному повышению чувствительности определений [13, 14, 16- [14,31,32,59]. Данное обстоятельство повышает селективность определений без использования методов хроматографии или капиллярного электрофореза, что значительно упрощает инструментальное обеспечение биомедицинских исследований, а также сокращает время их выполнения.…”