About the Presence of a Circulating Anti-Alkaline Phosphatase Antibody in a Trisomy 21 Patient’s Serum

Abstract

An electrophoretically slow-moving alkaline phosphatase was found in the serum of a 17-year-old patient with Down’s syndrome. Immunological and biochemical studies suggested that this abnormal enzyme pattern consisted of a complex of liver/bone isoenzyme with K-type immunoglobulins A and G.