Aborder la santé mentale à travers l’action intersectorielle dans le contexte de la COVID-19 et de l’agenda 2030 pour le développement durable

Ruggiero, Erica Di

doi:10.1177/17579759221122711

Cited by 1 publication

(2 citation statements)

References 3 publications

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“…Finally, the hemoglobin content of supernatant was estimated at 540 nm. The following formula was used to calculate the inhibition percentages of hemolysis: Inhibition (%) = [(AbsC − AbsS)/AbsC] × 100 (5) AbsC is the absorbance of the control tube (distilled water) and AbsS is the absorbance of the tube containing the extract or diclofenac.…”

Section: Hypotonic-induced Hemolysismentioning

confidence: 99%

“…As proof, the COVID-19 pandemic is a concrete and recent example. The evolution of the SARS-CoV-2 infection into severe forms, resulting in disproportionate inflammatory host responses, caused severe disruptions to health systems worldwide, leading to significant socio-economic destabilizations [ 5 , 6 , 7 ]. On the other hand, the production of reactive oxygen species during the inflammatory process is a normal reaction of the body in response to infection or tissue damage [ 8 ].…”

Section: Introductionmentioning

confidence: 99%

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Pentaclethra eetveldeana Leaves from Four Congo-Brazzaville Regions: Antioxidant Capacity, Anti-Inflammatory Activity and Proportional Accumulation of Phytochemicals

N’goka,

Oyegue Liabagui,

Sima Obiang

et al. 2023

Plants

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Oxidative stress and inflammation play a key role in the occurrence of neurodegenerative diseases. Traditionally, Pentaclethra eetveldeana leaves are used in dementia treatment. Therefore, this study aimed to evaluate the antioxidant and anti-inflammatory activities as well as the phytochemical composition of Pentaclethra eetveldeana leaves from four Congo-Brazzaville regions. The 1.2-diphenyl-1-picrylhydrazyl radical-scavenging, β-carotene bleaching and molybdenum reduction assays were used to assess the antioxidant activity. The protein denaturation and erythrocyte membrane stabilization tests were used to analyze the anti-inflammatory activity. Phytochemical screening, the quantification of polyphenols by spectrophotometry, as well as the determination of extraction yields were carried out. It was found that the extracts reduced molybdenum; furthermore, compared to ascorbic acid, they showed better antiradical activity and inhibited lipid peroxidation. Moreover, globally, the membrane-stabilizing power of the aqueous extracts was superior or comparable to diclofenac, while the same extracts were less effective for the inhibition of denaturation. All of the aqueous extracts contained polyphenols, saponins, alkaloids, anthraquinones, reducing sugar and cardiotonic glycosides. The total polyphenols, tannins and proanthocyanidins are produced proportionally from one region to another. Finally, the leaves from Brazzaville and Boundji contain flavonols, while those from Makoua and Owando contain flavones. Thus, Pentaclethra eetveldeana leaves contribute to traditional dementia treatment through their antioxidant and anti-inflammatory properties.

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Section: Hypotonic-induced Hemolysismentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%