Abordagem clínica dos distúrbios do equilíbrio ácido-base

Carlotti, Ana P. C. P.

doi:10.11606/issn.2176-7262.v45i2p244-262

Cited by 5 publications

(5 citation statements)

References 8 publications

(69 reference statements)

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“…The decrease in pH, HCO 3 and pCO 2 was classified as metabolic acidosis and decreased HCO 3 concentration results from the increase in the H + concentration (that decreases the pH). As a compensatory physiological response in an attempt to return to the normal pH is to eliminate carbon dioxide (CO 2 ) by pulmonary ventilation, decreasing the blood pCO 2 concentration (MARLIN & NANKERVIS, 2002;CARLOTTI, 2012). Similar results were reported by SILVA et al (2013) and BARBOSA et al (2016) who observed reduced pH and HCO 3 in horses due to the lactic acid increased in function of anaerobic exercise (post exercise metabolic acidosis).…”

Section: Resultsmentioning

confidence: 62%

“…The reduction in the HCO 3 concentration was due to the need of buffering by these increased H + protons (MARLIN & NANKERVIS, 2002), justifying their reduction at T1 and without full recomposition to normal concentrations in T2, which lowered the pH at T2 (Table 1). Decrease in cBase at T1 (P<0.05) may have occurred due to the reduction of HCO 3 -, because this is the most quantitative and important H + buffer in the organism (CARLOTTI, 2012), confirming that the variation in the cBase can accompany the HCO 3 direction variation in horses after exercise (KUPCZYNSKI e SPITALNIAK, 2015;LINHARES et al, 2017).…”

Section: Time -------------------------------------------------------mentioning

confidence: 84%

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Exercise training session-induced metabolic acidosis in barrel racing horses

et al. 2020

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In horses, acid-base balance disorders are common after intense exercise, with metabolic acidosis being the most common after high intensity and short duration exercise. Understanding the processes that cause them is fundamental for procedures, which aimed to improve the physical fitness of horses for athletic purposes, with fewer changes in homeostasis. The present study assessed the effect of barrel racing on acid base balance in Quarter Horse, at the following times: T0 - immediately before training; T1 - immediately after the end of the second course; T2 - one hour after the end of the second course. In T1, there was decrease (P<0.05) in the pH, HCO3 -, pCO2, cBase, tCO2 and strong ion difference concentrations, while the plasma lactate and anion gap increased (P<0.05). It was concluded that barrel racing training caused transient metabolic acidosis in the horses, and hyperlactatemia was still present after an hour of rest.

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Section: Resultsmentioning

confidence: 62%

Section: Time -------------------------------------------------------mentioning

confidence: 84%

Exercise training session-induced metabolic acidosis in barrel racing horses

et al. 2020

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“…Nos casos de acidose metabólica, deve ser avaliado se há compensação respiratória através da diminuição do valor da PCO2, para isto, é utilizada a fórmula de winter PCO2: 1,5 x [HCO3] + 8 ± 2. Nos casos de não compensação, significa dizer que há presença de distúrbios secundários, ou alcalose ou acidose respiratória, para isto, deve ser realizados ajustes na frequência respiratória (FR) no ventilador mecânico, utilizando-se a fórmula da FR desejada 10 . para a estimativa da PCO2 através da utilização da fórmula PCO2 esperada= 0,7 x [HCO3] + 20 (variação de +/-5).…”

Section: Stepunclassified

Fisioterapia No Câncer De Cabeça E Pescoço: Uma Proposta De Tratamento Na Unidade De Terapia Intensiva – Estudo De Revisão

Xavier¹,

Gomes²,

Matos³

et al. 2022

CPAH

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Com os diversos avanços na pesquisa cientifica e no tratamento de pacientes oncológicos, a probabilidade de recuperação e cura da doença bem como de seus efeitos deletérios na unidade de terapia intensiva (UTI) cresce e se traduz em um novo contexto de busca pela melhora da relação saúde e doença. A fisioterapia nas unidades de terapia intensiva oncológicas baseada inteiramente em evidências clínicas, protocolos normativos e padronizados torna a terapia segura e eficaz, o que favorece a recuperação e/ou taxa de sobrevida. O objetivo deste trabalho é a construção de uma proposta terapêutica sobre a abordagem em pacientes com câncer de cabeça e pescoço na UTI, baseando-se nas mais diversas pesquisas científicas que norteiam este contexto de saúde e doença, através da análise de literaturas relevantes nacionais e internacionais.

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“…When the concentration of H + in the blood increases (pH < 7.40), acidemia occurs, which may be secondary to metabolic or respiratory acidosis. Metabolic acidosis is the result of a process that increases the concentration of H + and decreases the concentration of HCO 3 in the blood (Carlotti, 2012) and insufficient HCO 3 inhibits the blood pH-lowering buffer effect due to changes in the gaseous exchange processes in the gills, which could be fatal.…”

Section: Experiments II -Chronic Tolerancementioning

confidence: 99%

Respiratory profile and gill histopathology of Carassius auratus exposed to different salinity concentrations

Silva

Ziemniczak

Bacha

et al. 2021

Semina: Ciênc. Agrár.

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The aim of this study was to evaluate the chronic salinity tolerance of Carassius auratus and the effects on blood parameters, gill morphology, and survival. In the first test, nine different concentrations (0.0, 0.5, 1.0, 2.5, 5.0, 10, 15, 20, and 25 g L-1) of NaCl were used with nine repetitions for 96 h. The survival of fish subjected to 15 g L-1 NaCl was 4 h, and 5 min at a concentration of 25 g L-1. The mortality of fish with 15 g L-1 NaCl was 100%. Morphological analyses of the gills showed hyperplasia of the coated cells in the interlamellar space and hypersecretion of mucus in fish exposed to 10 g L-1 of NaCl. At concentrations of 20 and 25 g L-1, necrosis of the support collagen caused the cells to detach from the lamellar structure mucosa. In the chronic test, two concentrations were used, with four replications containing nine fish in each aquarium for a period of 21 days. Blood samples and gills from the fish were collected, and it was observed that the fish showed a decrease in the concentration of bicarbonate (NaHCO3) in the blood, indicating hypernatremia. Acute exposure of C. auratus to sodium chloride (NaCl) should be at a maximum of 10 g L-1 of NaCl, after which level there would be a loss in animal performance and/or mortality. Chronic exposure to 5 g L-1 of NaCl promotes acidemia, ionic imbalance, and pathological changes in the gills; therefore, it is not recommended.

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Abordagem clínica dos distúrbios do equilíbrio ácido-base

Cited by 5 publications

References 8 publications

Exercise training session-induced metabolic acidosis in barrel racing horses

Exercise training session-induced metabolic acidosis in barrel racing horses

Fisioterapia No Câncer De Cabeça E Pescoço: Uma Proposta De Tratamento Na Unidade De Terapia Intensiva – Estudo De Revisão

Respiratory profile and gill histopathology of Carassius auratus exposed to different salinity concentrations

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