2022
DOI: 10.29309/tpmj/2022.29.11.6951
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ABO discrepancy in pediatric lymphomas and solid organ tumors.

Abstract: Objective: To determine the frequency of ABO discrepancies in pediatric patients of lymphoma and solid organ tumors and to categorize these discrepancies and their resolution. Study Design: Cross-sectional study. Setting: Department of Hematology & Transfusion Medicine, The University of Child Health Sciences & The Children’s Hospital, Lahore. Period: November 2020 to September 2021. Material & Methods: ABO blood group discrepancies were assessed by tube method of blood grouping, using antisera A, … Show more

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Cited by 2 publications
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“…In routine testing, both A1 and A2 are strongly agglutinated by anti-A antiserum but problem arises when A2 blood group individuals develop anti-A1 antibody which can cause discrepancies in blood grouping. 5 …”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…In routine testing, both A1 and A2 are strongly agglutinated by anti-A antiserum but problem arises when A2 blood group individuals develop anti-A1 antibody which can cause discrepancies in blood grouping. 5 …”
Section: Introductionmentioning
confidence: 99%
“…In routine testing, both A1 and A2 are strongly agglutinated by anti-A antiserum but problem arises when A2 blood group individuals develop anti-A1 antibody which can cause discrepancies in blood grouping. 5 When anti-A1 is active at body temperature, though rare, extensive destruction of A1 cells in vivo can occur and has been documented to cause severe hemolytic transfusion reaction. It is also important in cases of organ transplant.…”
Section: Introductionmentioning
confidence: 99%
“…Group I represents missing antibodies, group II is associated with unpredicted reaction due to weak antigens, group III demonstrates rouleaux formation and pseudo-aggluti-nation, group IV is associated with autoantibodies and polyagglutination. 2,3 In haematological malignancies and epigenetic variations of group A and B transferases the erythrocyte antigen genes expression might be lost. 4 Tumour cells were reported to secrete serum soluble blood group substances.…”
Section: Introductionmentioning
confidence: 99%