ABO Blood Types and Risk of Testicular Cancer in Turkish Population: Preliminary Results

Abstract

ABO blood type has been reported to be associated with various types of cancer such as lung cancer, prostate cancer, bladder cancer and pancreatic adenocarcinoma. We aimed to determine whether there is a relationship between ABO blood subtypes and testicular cancer incidence in Turkish population. Materials and Methods: We retrospectively analyzed the medical records of all patients who underwent inguinal orchiectomy in our department between 2008 and 2018. Results: A total of 138 patients were included in the study. The age of the patients ranged from two to 67 years, with a mean age of 32.9±10.9 years. Of the 138 participants, 45 (32.6%) had blood type A, 27 (19.6%) had blood type B, 50 had blood type O (36.2%) and 16 (11.6%) had blood type AB. One hundred and twenty-five patients (90.6%) were Rhesus (+) and 13 patients (9.4%) were Rhesus (-). There was no statistically significant difference between ABO blood subtypes according to testicular pathology (p=0.713). Interestingly, the percentage of patients with AB blood subtype was the lowest. Conclusion: These results suggest that Turkish men with O blood subtype and Rh (+) are prone to develop testicular cancer. However, these findings should be supported by further studies conducted with a large number of participants.