ABO blood groups in hematologic malignancies

Janardhana, Vijayalakshmi; Propert, David N.; Green, Ralph E.

doi:10.1016/0165-4608(91)90016-n

Cited by 22 publications

(22 citation statements)

References 11 publications

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“…Numerous studies show that the percentage of ABO and Rh blood types was found to be quite different in different samples of patients [18][19][20][21][22][23][24][25]. According to those findings, we assume that certain connection between predisposition to CDH and frequencies of ABO and Rh blood types exists.…”

Section: Introductionmentioning

confidence: 50%

Genetic Variability in the Group of Patients with Congenital Hip Dislocation

Cvjetićanin¹,

Marinković²

2005

Russ J Genet

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Our study of genetic homozygosity degree includes an analysis of the presence, distribution, and individual combination of 20 selected genetically controlled morphophysiological traits in the group of patients ( N = 93) with congenital hip dislocation (CDH) and in control sample consisting of schoolchildren from Belgrade ( N = 200). Assuming that CDH is a genetically controlled disease, we made a hypothesis that an increased homozygosity level, as well as the changed variability among the patients, could be a population-genetic parameter for the prediction of the illness. Taking into consideration our experience, as well as the experience of numerous scientists who studied the nature of the inheritance of mono-and oligogenically controlled qualitative traits, we applied a methodology to estimate the proportion of such homozygously recessive characters (HRC-TEST). This population-genetic study did not only show statistically significant difference of the middle values of genetic homozygosity (CDH: 7.1 ± 0.2; control: 5.2 ± 0.1), but of the differences in the type of distribution too, as well as the differences in the presence of certain individual combinations of such traits. The described methodology can be used in further analyses, with hope that it can be applied as an early prognosis for decreased resistance to different diseases.The frequencies of ABO blood types in the sample of CDH patients were similar to the average value of the Serbian population, while the percentage of blood group A is slightly increased. Comparing frequencies of Rh blood groups, there is no difference between tested samples. HUMAN GENETICS* This text was submitted by the authors in English.

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Section: Introductionmentioning

confidence: 50%

Genetic Variability in the Group of Patients with Congenital Hip Dislocation

Cvjetićanin¹,

Marinković²

2005

Russ J Genet

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“…Many published data from large cohort studies from different parts of the world suggest low incidence of many malignancies 16 28 and acute leukaemia. 29 Blood group O also appears to exert a protective effect by preventing the growth and spread of tumors and being associated with longer survival times in cancer patients. 30 The following will correlate our finding to, and might explain, the above finding.…”

Section: Discussionmentioning

confidence: 99%

Higher frequency of secretor phenotype in O blood group – its benefits in prevention and/or treatment of some diseases

Jaff¹

2010

IJN

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ABO blood groups and secretor status are important in clinical and forensic medicine and in relation to some diseases. There are geographic and racial differences in their frequencies, but the frequency of secretor status in different ABO blood group systems has not been determined yet. Therefore, the aim of this study was mainly to determine this point. Blood and saliva from 762 randomly selected apparently healthy adult individuals (480 men and 282 women) were examined to determine their ABO and Rhesus blood groups by standard conventional methods, and their secretor status by using Lewis blood grouping and/or hemagglutination inhibition test of saliva. Results showed that 76.1% of the study population were ABH blood group antigens secretors and 23.9% were nonsecretors. The frequencies of secretor status in different ABO blood groups were 70.1% in group A, 67.8% in group B, 67.9% in group AB, and 88.3% in group O. In conclusion, blood group O individuals have significantly higher frequency of secretor status than non-O blood group individuals. This finding would be beneficial to them, protecting them, at least partially, from certain malignancies or allowing them to have less aggressive disease, and this finding might be useful in enhancing further studies and research in this direction.

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“…In India and Western countries, many workers have tried to find out the relationship between ABO blood group and various systemic diseases, and the results showed that some diseases like dental caries,[4] salivary gland tumors,[5] chicken pox,[6] malaria,[7] oral cancer,[8] hematological malignancies,[9] ischemic heart disease,[10] cholera,[11] etc., had significant association.…”

Section: Introductionmentioning

confidence: 99%

Correlation between "ABO" blood group phenotypes and periodontal disease: Prevalence in south Kanara district, Karnataka state, India

Pai

Dayakar

Mulki

et al. 2012

J Indian Soc Periodontol

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Background:The correlation between certain systemic diseases and ABO blood group is a well-documented fact. The association between periodontal disease and ABO blood group is not studied in relation to a specific geographic location. Here is a study conducted on a group of patients belonging to South Kanara district of Karnataka state.Materials and Methods:A total of 750 subjects aged between 30and 38 years belonging to South Kanara district were selected on random basis. The study subjects were segregated into healthy/mild gingivitis, moderate/severe gingivitis, and periodontitis group, based on Loe and Silness index and clinical attachment loss as criteria. The study group was further categorized and graded using Ramfjord's periodontal disease index. Blood samples were collected to identify ABO blood group.Results:Prevalence of blood group O was more in South Kanara district, followed by blood groups B and A, and the least prevalent was AB. The percentage distribution of subjects with blood groups O and AB was more in healthy/mild gingivitis group (group I) and moderate/severe gingivitis group (group II), while subjects with blood groups B and A were more in periodontitis group III. There was increased prevalence of subjects with blood groups O and AB with healthy periodontium, while subjects with blood groups B and A showed inclination toward diseased periodontium.Conclusion:There is a correlation existing between periodontal disease and ABO blood group in this geographic location. This association can be due to various blood group antigens acting as receptors for infectious agents associated with periodontal disease. This broad correlation between periodontal disease and ABO blood group also points toward susceptibility ofthe subjects with certain blood groups to periodontal disease.

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ABO blood groups in hematologic malignancies

Cited by 22 publications

References 11 publications

Genetic Variability in the Group of Patients with Congenital Hip Dislocation

Genetic Variability in the Group of Patients with Congenital Hip Dislocation

Higher frequency of secretor phenotype in O blood group – its benefits in prevention and/or treatment of some diseases

Correlation between "ABO" blood group phenotypes and periodontal disease: Prevalence in south Kanara district, Karnataka state, India

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ABO blood groups in hematologic malignancies

Cited by 22 publications

References 11 publications

Genetic Variability in the Group of Patients with Congenital Hip Dislocation

Genetic Variability in the Group of Patients with Congenital Hip Dislocation

Higher frequency of secretor phenotype in O blood group &ndash; its benefits in prevention and/or treatment of some diseases

Correlation between "ABO" blood group phenotypes and periodontal disease: Prevalence in south Kanara district, Karnataka state, India

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Higher frequency of secretor phenotype in O blood group – its benefits in prevention and/or treatment of some diseases