ABO blood groups and risk of deep venous thromboembolism in Chinese Han population from Chaoshan region in South China

Yu, Min; Wang, Cantian; Chen, Tingting; Hu, Shuang; Yi, Kaihong; Tan, Xuerui

doi:10.15537/smj.2017.4.16349

Cited by 7 publications

(7 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The potential roles of ABO blood groups in DVT have also been addressed. There is a higher risk for DVT in patients with non-O blood groups than in paients with blood group O [3][4][5]. More recently, we found that the patients in the O blood group had lower warfarin dose requirements than those in the A, B and AB blood groups [6].…”

Section: Introductionmentioning

confidence: 70%

Effect of ABO Blood Groups, Age and Gender on Coagulation Assays in Patients With Acute Deep Vein Thrombosis

Chen

Deng

et al. 2021

Preprint

Self Cite

View full text Add to dashboard Cite

Background: Genetic polymorphisms, age, gender and body weight are major determinants of warfarin dose requirements. Our previous study showed that patients with non-O blood groups required higher doses of warfarin than those with O blood groups. However, the underling mechanism was not well known.Objectives: The study aimed to investigate the influence of ABO blood group, age and gender on the values of coagulation tests in patients with acute deep vein thrombosis in Chinese Han population.Methods: A retrospective study was conducted in the First Affiliated Hospital of Shantou University Medical College in Southern China. Two hundreds and 35 patients with confirmed diagnosis of acute deep vein thrombosis were included. Coagulation tests were determined.Results: Of 235 patients with acute deep vein thrombosis of lower extremities, 70 patients had blood group A (29.79%), 71 patients had blood group B (30.21%), 30 patients had blood group AB (12.77%), and 64 patients had blood group O (27.23%). The study showed no difference about coagulation tests among the patients with different blood groups. Coagulation tests were not affected by age and gender.Conclusion: Our study showed that ABO blood group, age and gender had no effects on coagulation tests in patients with acute deep vein thrombosis

show abstract

Section: Introductionmentioning

confidence: 70%

Effect of ABO Blood Groups, Age and Gender on Coagulation Assays in Patients With Acute Deep Vein Thrombosis

Chen

Deng

et al. 2021

Preprint

Self Cite

View full text Add to dashboard Cite

show abstract

“…Although inconsistently, these links were reported in numerous conditions, including nonalcoholic fatty liver disease, congenital heart disease, deep venous thrombosis, malaria severity, type 2 diabetes, and different cancers. [29][30][31][32][33][34] Regarding brain tumors, non-O blood groups were repeatedly associated with increased risk and poor prognosis. 24,25,27 In the current study, when compared to pediatric O blood group patients, AB group patients had a 2.79fold higher risk of developing primary brain tumors.…”

Section: Discussionmentioning

confidence: 99%

AB Blood Group Confers Higher Risk for Primary Brain Tumors in Pediatrics

Shudifat¹,

Suqi²,

Soub³

et al. 2021

RMHP

View full text Add to dashboard Cite

Purpose Our current study investigates the relationship between ABO blood groups and brain tumor incidence in the Jordanian pediatric population in a case-controlled manner. Patients and Methods This case-control study targeted pediatric primary brain tumor patients and tumor-free controls. Cases included patients younger than 18 when given a histologically confirmed diagnosis with a primary brain tumor, ascertained from two tertiary hospitals in Jordan. Controls were age- and gender-matched to cases and acquired from JUH pediatric clinics, with an exclusion for all patients with a personal history of tumors. Through using available records and calling guardians, our team obtained patients’ and controls’ blood groups. Results Our case control included 81 (35.4%) pediatric primary brain tumor patients and age- and gender-matched tumor-free controls 148 (64.6%). When compared to O blood group, patients with A and B blood groups were not at higher risk of developing pediatric primary brain tumors (P=0.742, P=1.000, respectively). However, Chi-square analysis revealed a 2.79-fold higher risk for pediatric primary brain tumors in AB blood group patients (P=0.024). Gender-specific analysis revealed a 3.42-fold higher risk for pediatric brain tumors in AB blood group males when compared to O blood group males. Conclusion This work represents the first published study on the association between blood groups and pediatric brain tumors. With future research with larger samples and control of confounding factors, AB blood group may become a more established risk factor for pediatric brain tumors, aiding in screening.

show abstract

“…Recently the relationships between ABO blood groups and DVT have been demonstrated. Compared with O blood group, there is higher risk of venous thromboembolism in non-O blood groups [12][13][14]. Furthermore, the blood group remarkably affected the anesthetic effects of propofol [17].…”

Section: Discussionmentioning

confidence: 99%

Effect of ABO blood groups on response to warfarin

Zou¹,

Wu²,

Chen³

et al. 2019

Preprint

Self Cite

View full text Add to dashboard Cite

Background: Numerous studies have demonstrated that patients with non-O blood groups have higher risk for venous thromboembolism than those with O blood group. However, it has remained unknown about the effect of ABO blood groups on warfarin dose requirements in patients receiving anticoagulation in Chinese Han population. The study aimed to investigate the influence of ABO blood groups on warfarin dose requirements in Chinese Han population. Methods: A retrospective study was conducted in the First Affiliated Hospital of Shantou University Medical College in Southern China. Three hundreds and 58 patients with confirmed diagnosis of deep venous thromboembolism and atrial fibrillation were included. Frequency of blood groups and warfarin dose requirements were determined. Results: Of 358 patients with deep venous thromboembolism and atrial fibrillation, 111 patients had blood group A (31.01%), 104 patinets had blood group B (29.05%), 20 patients had blood group AB (5.59%), and 123 patients had blood group O (34.36%). The patients with O blood group had a lower warfarin dose requirements compared with those with A, B and AB blood group. Conclusion: Our study showed that patients with non-O blood groups require higher doses of warfarin.

show abstract

ABO blood groups and risk of deep venous thromboembolism in Chinese Han population from Chaoshan region in South China

Cited by 7 publications

References 18 publications

Effect of ABO Blood Groups, Age and Gender on Coagulation Assays in Patients With Acute Deep Vein Thrombosis

Effect of ABO Blood Groups, Age and Gender on Coagulation Assays in Patients With Acute Deep Vein Thrombosis

AB Blood Group Confers Higher Risk for Primary Brain Tumors in Pediatrics

Effect of ABO blood groups on response to warfarin

Contact Info

Product

Resources

About