ABO blood group, hepatitis B viral infection and risk of pancreatic cancer

Wang, De Shen; Chen, Dong Liang; Ren, Chao; Wang, Zhi Qiang; Qiu, Miao Zhen; Luo, Hui; Zhang, Dong Sheng; Wang, Feng Hua; Li, Yu Hong; Xu, Rui‐Hua

doi:10.1002/ijc.26376

Cited by 116 publications

(100 citation statements)

References 45 publications

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“…After review, two studies were excluded with the following reasons: a study of HCV infection (El-Serag et al, 2009); a case report (Yoo et al, 2009). Thus, eight articles met the inclusion criteria (de Gonzalez et al, 2008;Hassan et al, 2008;Gordon et al, 2009;Iloeje et al, 2009;Hong et al, 2010;Zhu et al, 2011;Ben et al, 2012;Wang et al, 2012), six of these studies were conducted only in East Asia (de Gonzalez et al, 2008;Iloeje et al, 2009;Hong et al, 2010;Zhu et al, 2011;Ben et al, 2012;Wang et al, 2012) and two in USA (Hassan et al, 2008;Gordon et al, 2009).…”

Section: Literature Search and Studies Characteristicsmentioning

confidence: 99%

“…There were a total of 302420 individuals in the included eight studies. In most of the studies (de Gonzalez et al, 2008;Hassan et al, 2008;Gordon et al, 2009;Zhu et al, 2011;Ben et al, 2012;Wang et al, 2012), pancreatic cancer was diagnosed according the histology. In other studies (Iloeje et al, 2009;Hong et al, 2010), pancreatic cancer is confirmed by histology or diagnosed by symptoms, signs and more than two types of imaging tools.…”

Section: Literature Search and Studies Characteristicsmentioning

confidence: 99%

“…Of these eight studies, five were conducted in a hospital-based case-control study design (Hassan et al, 2008;Hong et al, 2010;Zhu et al, 2011;Ben et al, 2012;Wang et al, 2012), three in cohort design (de Gonzalez et al, 2008;Gordon et al, 2009;Iloeje et al, 2009 al., 2012), two in USA (Hassan et al, 2008;Gordon et al, 2009). The selection of controls varied substantially.…”

Section: Quality Evaluation Of Included Studiesmentioning

confidence: 99%

“…The selection of controls varied substantially. Controls were acute patients (Hassan et al, 2008;Hong et al, 2010;Zhu et al, 2011;Ben et al, 2012;Wang et al, 2012), patients with active HBV infection (Gordon et al, 2009), or volunteers for checkup (de Gonzalez et al, 2008;Gordon et al, 2009;Iloeje et al, 2009). All groups of controls appeared to be selected on the basis of convenience.…”

Section: Quality Evaluation Of Included Studiesmentioning

confidence: 99%

“…Also, some cohort and case-control studies (de Gonzalez et al, Lei Li 1,3 , Bo Wu 2 , Li-Bo Yang 3 , Guan-Cheng Yin 3 , Ji-Yong Liu 1 * 2008; Hassan et al, 2008;Iloeje et al, 2009;Gordon et al, 2009;Hong et al, 2010;Zhu et al, 2011;Wang et al, 2012;Ben et al, 2012) have been conducted to estimate the relationship between chronic hepatitis B virus infection and pancreatic cancer. But the results were controversial.…”

Section: Introductionmentioning

confidence: 99%

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Chronic Hepatitis B Virus Infection and Risk of Pancreatic Cancer: A Meta-analysis

Wu²,

Yang³

et al. 2013

Asian Pacific Journal of Cancer Prevention

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Section: Literature Search and Studies Characteristicsmentioning

confidence: 99%

Section: Literature Search and Studies Characteristicsmentioning

confidence: 99%

Section: Quality Evaluation Of Included Studiesmentioning

confidence: 99%

Section: Quality Evaluation Of Included Studiesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Chronic Hepatitis B Virus Infection and Risk of Pancreatic Cancer: A Meta-analysis

Wu²,

Yang³

et al. 2013

Asian Pacific Journal of Cancer Prevention

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ABO blood group and nasopharyngeal carcinoma risk in a population of Southeast China

Sheng

Sun

Zhang

et al. 2013

Intl Journal of Cancer

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Previous studies found that the ABO blood type alters the individual susceptibility of some malignancies. However, whether such an association exists between ABO blood type and nasopharyngeal carcinoma (NPC) remains unknown. A case-control study was conducted, with 1,538 patients who had NPC and 1,260 cancer-free controls. The association between ABO blood type and NPC incidence was evaluated using unconditional logistic regression analysis. Compared with subjects with blood type O, a relatively higher risk was observed among cases with blood types A or AB, with ORs (95% confidence interval) of 1.287 (1.072 2 1.545), p 5 0.007 and 1.390 (1.007 2 1.919), p 5 0.045, respectively, after adjusting for gender, age, smoking status and family history of cancer. The rate of distant metastasis was significantly higher among male patients with blood type A than in patients with non-A blood types (6.8 vs. 3.5%, p 5 0.027). Our results suggest that blood types A or AB is associated with an increased risk of NPC. Further studies are needed to confirm this association and to explore the mechanisms involved.

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Evaluation of risk factors for extrahepatic cholangiocarcinoma: ABO blood group, hepatitis B virus and their synergism

Zhou

et al. 2013

Int. J. Cancer

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Little is known about the role of association between ABO blood group and development of extrahepatic cholangiocarcinoma (ECC) through effects on hepatitis B viral (HBV) infection. Our aim was to address this question using a matched case-control study in Southern China.We prospectively analyzed 239 ECC patients, and 478 age-and sex-matched controls in Sun Yat-sen Memorial Hospital of Sun Yat-sen University from 1999 to 2011. Information on ABO blood group, HBV infection and other clinicopathologic factors was collected. Adjusted odds ratios (AORs) and the corresponding 95% confidence intervals (CIs) were computed from unconditional logistic regression models, adjusted for major confounding factors. The estimated AORs were as follows: A blood group, 1.784; HBsAg1/HbcAb1, 1.848 and HBsAg2/HbcAb1, 1.501. The A blood type had a significant effect on modifying the risk of ECC among subjects with HBsAg1/HbcAb1 (AOR 3.795, 95% CI 1.427-10.090). ECC patients with A blood group were more common in younger subjects, and a lower proportion of serum CA-125 and CA19-9 elevation in patients with blood type A was found. Our study suggests an association between A blood type, HBV infection and ECC risk, and a synergism between A blood type and HBV infection in the development of ECC.Cholangiocarcinoma (CC) is a malignant neoplasm of the biliary-duct system accounting for 10-25% of the primary hepatic malignancies worldwide.1 Recent study showed that the incidence and mortality rates of CC have been increasing worldwide including China.2-6 Although several risk factors for CC, including parasitic infection, primary sclerosing cholangitis, anatomical abnormalities and hepatolithiasis, have been established, some potential factors such as hepatitis virus infection and host genetic polymorphisms remain debating. 7 Meanwhile, data showed that potential risk factors might have different effect on CC, depending on the anatomical site. 8 The role of HBV in ECC is not entirely clear, and the related studies have different conclusions. 7 The prevalence rate of infection with hepatitis B virus (HBV) varies widely among different parts of the world; it can range from near zero to more than 10%.9 China is a typical highly endemic area of HBV infection. The effect of HBV infection on the incidence, age or sex distribution and clinicopathologic parameters of intrahepatic cholangiocarcinoma (ICC) has been documented by many studies, but the role of HBV in the development of extrahepatic cholangiocarcinoma (ECC) in viral hepatitis B endemic areas was less reported and remains to be addressed.Furthermore, several genome-wide studies demonstrated that ABO blood group antigens may alter the systemic inflammatory response. And, blood antigens are also known

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ABO blood group, hepatitis B viral infection and risk of pancreatic cancer

Cited by 116 publications

References 45 publications

Chronic Hepatitis B Virus Infection and Risk of Pancreatic Cancer: A Meta-analysis

Chronic Hepatitis B Virus Infection and Risk of Pancreatic Cancer: A Meta-analysis

ABO blood group and nasopharyngeal carcinoma risk in a population of Southeast China

Evaluation of risk factors for extrahepatic cholangiocarcinoma: ABO blood group, hepatitis B virus and their synergism

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