Abstract:Objective: The classical osteoporotic signaling pathways include the four key genes(LRP5, Runx2, Osterix, and RANKL) influencing the regulation of osteogenesis and osteoclastogenesis. This study investigates the variations of these four genes in bone specimens associated with fractures in osteoporotic rats.
Methods: Osteoporotic rats (Ovariectomised rats) as an osteoporotic group were randomly divided into three groups-group A, group B, and group C. Non-osteoporotic rats as control group were likewise divided … Show more
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