Abnormal Uterine Bleeding

Lebduska, Elena; Beshear, Deidra; Spataro, Brielle

doi:10.1016/j.mcna.2022.10.014

Cited by 6 publications

(4 citation statements)

References 31 publications

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“…MCDs affect 75% of young women in developed and developing countries and constitute the majority of diseases of women of childbearing age [3]. These conditions, especially menorrhagia, are a serious reason for consulting a doctor [4]. MCDs not only impair the reproductive capacity of young women, but are associated with various pathological conditions, in particular with anemia, thyroid gland dysfunction, etc.…”

Section: огляди літератури / Literature Reviewsmentioning

confidence: 99%

Current State of the Problem of Menstrual Cycle Disorders in Women of Reproductive Age With Undifferentiated Connective Tissue Dysplasia (Literature Review)

Rakytianskyi

2024

VPBM

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Section: огляди літератури / Literature Reviewsmentioning

confidence: 99%

Current State of the Problem of Menstrual Cycle Disorders in Women of Reproductive Age With Undifferentiated Connective Tissue Dysplasia (Literature Review)

Rakytianskyi

2024

VPBM

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“…Abnormal uterine bleeding (AUB) is a common gynecological disease, usually manifesting in excessive menstruation, prolonged menstruation, and irregular vaginal bleeding, which seriously affects the work efficiency and quality of life of patients. Modern medicine holds that AUB is caused by neuroendocrine disorders regulated by the hypothalamic–pituitary–ovary axis (HPOA) [ 1 ]. At present, estrogen and progesterone drugs are often used in clinical treatment.…”

Section: Introductionmentioning

confidence: 99%

Parsing the Q-Markers of Baoyin Jian to Treat Abnormal Uterine Bleeding by High-Throughput Chinmedomics Strategy

Ren

Liu

et al. 2023

Pharmaceuticals

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Abnormal uterine bleeding (AUB) is a common and frequently occurring disease in gynecology, seriously threatening women’s health. Baoyin Jian (BYJ) is a classical prescription for treating AUB. However, the lack of quality control standards of BYJ for AUB have limited the development and applications of BYJ. This experiment aims to explore the mechanism of action and screen the quality markers (Q-markers) of BYJ against AUB through the Chinmedomics strategy to improve the quality standards of Chinese medicine and provide scientific basis for its further development. BYJ has hemostatic effects in rats, as well as the ability to regulate the coagulation system following incomplete medical abortion. According to the results of histopathology, biochemical indexes and urine metabolomics, a total of 32 biomarkers of ABU in rats were identified, 16 of which can be significantly regulated by BYJ. Using traditional Chinese medicine (TCM) serum pharmacochemistry technology, 59 effective components were detected in vivo, of which 13 were highly correlated with efficacy, and 9 components, namely catalpol, rehmannioside D, paeoniflorin, berberine, phellodendrine, baicalin, asperosaponinVI, liquiritin, and glycyrrhizic acid, were screened out as the Q-markers of BYJ based on the “Five Principles” of Q-markers. In sum, BYJ can effectively alleviate abnormal bleeding symptoms and metabolic abnormalities in AUB rats. The study shows that Chinmedomics is an effective tool for screening Q-markers and provides scientific support for the further development and clinical use of BYJ.

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“…Причинами АМК могут быть различные нарушения и заболевания [7,8]. Наиболее распространенными из них являются гормональный дисбаланс, гипокоагулопатии, последствия заболеваний, особенно печени и почек, воспалительных процессов гениталий [9,10].…”

Section: Introductionunclassified

Abnormal Uterine Bleeding in Adolescence Burdened with Severe Anemia: Clinical Case

Adamyan,

Sibirskaya,

Karachentsova

et al. 2023

Vopr. sovr. pediatr.

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Background. Abnormal uterine bleeding (AUB) in adolescence is one of the urgent problems of medicine nowadays. It is on the 2nd place among all the reasons for hospitalization in gynecological departments, and its incidence among girls during puberty is 50%. Clinical case description. This is the clinical case of 15-year-old girl admitted to the gynecology department with complaints on long-lasting bloody vaginal discharge, fatigue, dizziness. The diagnosis of «abnormal uterine bleeding in adolescence» burdened with iron deficiency anemia (IDA) was established according to laboratory and instrumental examinations. The patient underwent RBC-transfusion with specific buffy coat and was administered with hormonal hemostatic and anti-anemic therapy. Conclusion. We can conclude (with reference to this observation and the reviewed literature) not only that IDA is one of the most common complications of AUB in adolescence, but also what management should be used in such clinical cases.

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Abnormal Uterine Bleeding

Cited by 6 publications

References 31 publications

Current State of the Problem of Menstrual Cycle Disorders in Women of Reproductive Age With Undifferentiated Connective Tissue Dysplasia (Literature Review)

Current State of the Problem of Menstrual Cycle Disorders in Women of Reproductive Age With Undifferentiated Connective Tissue Dysplasia (Literature Review)

Parsing the Q-Markers of Baoyin Jian to Treat Abnormal Uterine Bleeding by High-Throughput Chinmedomics Strategy

Abnormal Uterine Bleeding in Adolescence Burdened with Severe Anemia: Clinical Case

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