Abnormal skin changes and unilateral vision loss after a tuberculin skin test

Abstract

The incidence of active tuberculosis (TB) in Canada is about 4.8 per 100 000 people, and latent TB affects more than 1.5 million people, in about 5%-10% of whom the disease will reactivate.• Tuberculin skin test (TST) is performed to diagnose latent TB, in the absence of clinical symptoms, and may cause an immune reaction that can, uncommonly, reactivate latent TB.

Acute relapse of Multiple Sclerosis (MS) in an adolescent patient after Tuberculin skin test (TST): a case report

“…Tuberculin Skin Test (TST) is based on a delayed-type hypersensitivity reaction in response to the exposure to the purified protein derivative (PPD) antigen. Some rare complications following TST in patients with and without tuberculosis (TB) have been previously reported, though none indicate an acute MS relapse (3)(4)(5). Here we report the relapse of a previously diagnosed and inactive MS in a 12-year-old girl with negative TST.…”