Abnormal papillary muscle morphology is independently associated with increased left ventricular outflow tract obstruction in hypertrophic cardiomyopathy

Kwon, Deborah; Setser, Randolph M.; Thamilarasan, Maran; Popović, Zoran V.; Smedira, Nicholas G.; Schoenhagen, Paul; García, Mario J.; Lever, Harry M.; Desai, Milind Y.

doi:10.1136/hrt.2007.118018

Cited by 144 publications

(104 citation statements)

References 31 publications

(30 reference statements)

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“…установили, что у пациентов с обструктивной ГКМП и переднеапикальной дисло-кацией папиллярных мышц и расщеплением головок папиллярных мышц отмечается более высокий гра-диент в ВТЛЖ в покое вне зависимости от толщины межжелудочковой перегородки [21].…”

Section: анатомия митрального клапана и папиллярных мышцunclassified

“…Митральная регургитация, вызванная передне-сис-толическим смещением створок МК, обычно имеет Таблица 1 Структурные и функциональные аномалии митрального клапана при гипертрофической кардиомиопатии [21] Папиллярные мышцы …”

Section: д) натяжение митрального клапана аномальной передней папилляunclassified

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Alcohol septal ablation: patient selection and rationality of its application

Kashtanov¹,

Chernyshev²,

Kardapoltsev³

et al. 2017

PKiK

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The article looks at some aspects of selecting patients with obstructive hypertrophic cardiomyopathy for alcohol septal ablation (ASA) procedure. Based on the world’s experience and in the context of evidence-based medicine, the current positions of ASA in complex treatment of obstructive hypertrophic cardiomyopathy are described. Received 29 September 2016. Accepted 9 January 2017.Funding: The study had no sponsorship.Conflict of interest: The authors declare no conflict of interest.Author contributionsData collection and analysis: Kashtanov M.G. Drafting the article: Kashtanov M.G. Critical revision: Kashtanov M.G., Idov E.M., Chernyshev S.D., Kardapoltsev L.V., Berdnikov S.V.

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Section: анатомия митрального клапана и папиллярных мышцunclassified

Section: д) натяжение митрального клапана аномальной передней папилляunclassified

Alcohol septal ablation: patient selection and rationality of its application

Kashtanov¹,

Chernyshev²,

Kardapoltsev³

et al. 2017

PKiK

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“…Özellikle anterior papiller kasın normal hastalara göre farklı yerleşimi gibi papiller kas anormalliklerinin yüksek oranda bulunması bu durumu destekler niteliktedir (47)(48)(49). Kardiyak MR mitral kapak ve papiller kas yapılarının değerlendirilmesinde, mitral ön yaprağın septuma temas noktasının tespitinde ve HKM ile karışabilecek SVÇY gradiyenti oluşturan tablolardan biri olan subaortik membranın tanısında da değerli bir yöntemdir.…”

Section: Sol Ventrikül çıKış Yolu Obstrüksiyonuunclassified

Hipertrofik kardiyomiyopatili hastaların risk sınıflandırmasında görüntüleme yöntemlerinin yeri

Tülüce¹,

Emren²,

Tülüce³

et al. 2015

Ege Tıp Dergisi

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Hipertrofik kardiyomiyopati (HKM) genetik geçişli bir kalp hastalığıdır. Genç sporcularda ani kardiyak ölümün (AKÖ) en sık nedenidir. Bu ölümlerin önlenebilmesi için hekimler büyük özen göstermektedir. Ani kardiyak ölüm açısından yüksek riskli hastalar implante edilebilen kardiyoverter defibrilatör tedavisi için adaydırlar. Ani kardiyak ölüm açısından yüksek riskli bu bireylerin saptanabilmesi için yapılan risk sınıflandırmasında kardiyak görüntüleme yöntemleri önemli bilgiler sağlamaktadır. Görüntüleme yöntemleri ile elde edilen bilgilerin doğru yorumlanması ve önlemlerin alınması bu hastalar için hayat kurtarıcı olması nedeniyle büyük önem taşımaktadır. Teknolojideki gelişmeler yüksek riskli hastaların erken tespitine önemli katkılar sağlamaktadır. Bu derlemede biz HKM'li hastaların risk sınıflandırmasında görüntüleme yöntemlerinin yeri ve önemini değerlendirdik.Anahtar Sözcükler: Hipertrofik kardiyomiyopati, ani kardiyak ölüm, kalp görüntüleme yöntemleri. Abstract Hypertrophic cardiomyopathy (HCM) is a genetic cardiac disorder. It is the most common reason of sudden cardiac death (SCD) in young athletes. Prevention of these deaths is

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“…In myectomy, it shows that the resection is restricted to the basal septum, ensuring greater gradient reduction 79 . In cases with severe obstruction and LV wall thickness slightly increased or normal, MRI detects structural anomalies of the mitral valve and/or papillary muscles responsible for the obstruction and which may be surgically corrected 21 . …”

Section: Magnetic Resonance Imagingmentioning

confidence: 99%

“…Fibrous adherences between the septum and papillary muscles, free wall of the LV or mitral apparatus pull this structure anteriorly, contributing to a higher degree of obstruction 20 . Anomalies of papillary muscles identified by magnetic resonance imaging (MRI), include thickening, bifid character and anterior apical displacement, are common in HCM and are connected to the higher prevalence of SAM and higher gradients, regardless of septum thickness 21 .…”

Section: Introductionmentioning

confidence: 99%

O diagnóstico da obstrução da via de saída do ventrículo esquerdo na cardiomiopatia hipertrófica

Mattos¹,

Torres²,

Rebelatto³

et al. 2012

Arq. Bras. Cardiol.

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Hypertrophic cardiomyopathy is a prevalent genetic disease characterized by left ventricular hypertrophy, presenting dynamic obstruction of outflow tract with subaortic gradient happening at rest in 30% of the cases. It is attributed to the intricate interaction between the anterior mitral leaflet, the interventricular septum and altered flow vectors generated in left ventricle along with changes in outflow tract geometry. Mitral regurgitation in varying degrees is found with or without association with structural deformities of the valve apparatus. The exercise echocardiogram evidences latent obstruction easily induced by exercise in 60 to 75% of nonobstructive forms. The determination of the gradient under this condition must be considered in routine investigation of patients with mild or no obstruction at rest. The evaluation of hypertrophic cardiomyopathy incorporates methods based on the ultrasound image, which, along with MRI, allow recognizing ventricular obstruction generating mechanisms, thus facilitating the diagnosis and management of obstructive and latent obstructive forms.

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Abnormal papillary muscle morphology is independently associated with increased left ventricular outflow tract obstruction in hypertrophic cardiomyopathy

Abstract: Patients with HCM with abnormal PM have a higher degree of resting LVOT gradient, which is independent of septal thickness.

Cited by 144 publications

References 31 publications

Alcohol septal ablation: patient selection and rationality of its application

Alcohol septal ablation: patient selection and rationality of its application

Hipertrofik kardiyomiyopatili hastaların risk sınıflandırmasında görüntüleme yöntemlerinin yeri

O diagnóstico da obstrução da via de saída do ventrículo esquerdo na cardiomiopatia hipertrófica

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