The magnetoresistance (MR) effect of the low-temperature phase of silver selenide ͑␣-Ag 2+␦ Se͒ is measured as a function of composition. Very small composition variations in the order of ⌬␦ =10 −6 are achieved by coulometric titration and can be performed simultaneously during the MR measurement. A homogeneous Ag 2+␦ Se shows an ordinary magnetoresistance (OMR) effect, which can be well described by the two-band model. For silver selenide with a heterogenous silver excess, we found quite a different MR behavior. Up to a minor silver excess of 1 ϫ 10 −4 Ͻ ␦ Ͻ 1 ϫ 10 −2 , a saturating negative MR effect, a linear positive MR effect, or a superposition of both can be measured. The microstructure of the silver-rich Ag 2+␦ Se determines its complicated MR behavior. A heterogeneous silver selenide with a larger silver excess ͑␦ Ͼ 10 −2 ͒ shows again an OMR effect.