Abnormal fetal growth is associated with gestational diabetes mellitus later in life: population‐based register study

Claesson, Rickard; Åberg, Anders; Maršál, Karel

doi:10.1080/00016340701207682

Cited by 35 publications

(25 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This study strengthens previous findings of increased risk of pregnancy complications in women born with low birth weights. 6,[8][9][10][11][12] An inverse relation between birth weight and risk of preeclampsia and of gestational diabetes has been shown in case-control and populationbased cohort studies. 8,21,22 In a large populationbased cohort study, Zetterström and colleagues 10 found an increased risk of preeclampsia among women born small for gestational age (v. appropriate weight for gestational age).…”

Section: Discussionmentioning

confidence: 99%

“…We performed normal logistic regressions using the 3 gestational age groups to obtain adjusted ORs and 95% confidence intervals (CIs). This analysis was done to distinguish the effect of preterm birth from the impact of confounding variables shown to be associated with increased risk of the pregnancy complications studied: small for gestational age and large for gestational age, 8,10 multiple pregnancy, maternal age of 25 years or older, 18 diagnosis of chronic hypertension, type 1 or 2 diabetes, and kidney disease. 19 The analyses were realized for (a) the risk of a pregnancy complication at least once during the study period (with the number of women affected as the unit of measurement and not the number of episodes; e.g., a woman with 3 pregnancies complicated by preeclampsia was included as 1 participant) and for (b) the risk of a pregnancy complication at the first live delivery.…”

Section: Discussionmentioning

confidence: 99%

“…[5][6][7] Furthermore, studies have shown that women born with low birth weights are at increased risk of gestational hypertension, preeclampsia and gestational diabetes. [8][9][10] However, many of these studies either have not taken into account gestational age or have a number of shortcomings, such as small sample, young population (mostly teenagers), degree of prematurity not specified or study population consisting mostly of late preterm births. 6,11,12 In the province of Quebec, weight and gestational age have been recorded in a registry for all births since 1976, and data on all hospital-based diagnoses have been collected since 1987.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Pregnancy complications among women born preterm

Boivin

Luo

Audibert

et al. 2012

CMAJ

View full text Add to dashboard Cite

Research CMAJBackground: Adults who were born with low birth weights are at increased risk of cardiovascular and metabolic conditions, including pregnancy complications. Low birth weight can result from intrauterine growth restriction, preterm birth or both. We examined the relation between preterm birth and pregnancy complications later in life. Methods:We conducted a population-based cohort study in the province of Quebec involving 7405 women born preterm (554 < 32 weeks, 6851 at 32-36 weeks) and a matched cohort of 16 714 born at term between 1976 and 1995 who had a live birth or stillbirth between 1987 and 2008. The primary outcome measures were pregnancy complications (gestational diabetes, gestational hypertension, and preeclampsia or eclampsia).Results: Overall, 19.9% of women born at less than 32 weeks, 13.2% born at 32-36 weeks and 11.7% born at term had at least 1 pregnancy complication at least once during the study period (p < 0.001). Women born small for gestational age (both term and preterm) had increased odds of having at least 1 pregnancy complication compared with women born at term and at appropriate weight for gestational age. After adjustment for various factors, including birth weight for gestational age, the odds of pregnancy complications associated with preterm birth was elevated by 1.95-fold (95% confidence interval [CI] 1.54-2.47) among women born before 32 weeks' gestation and 1.14-fold (95% CI 1.03-1.25) among those born at 32-36 weeks' gestation relative to women born at term. Interpretation:Being born preterm, in addition to, and independent of, being small for gestational age, was associated with a significantly increased risk of later having pregnancy complications. Abstract

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

Pregnancy complications among women born preterm

Boivin

Luo

Audibert

et al. 2012

CMAJ

View full text Add to dashboard Cite

show abstract

“…When the baby is female, exposure to maternal hyperglycaemia in utero might increase her own risk of subsequently developing GDM in her own pregnancies [6]. Shortly after delivery, the glucose values are generally restored to normal, but women with GDM have a sevenfold increased risk of developing T2DM [7].…”

Section: Introductionmentioning

confidence: 99%

Glucose Intolerance after a Recent History of Gestational Diabetes

Benhalima

Leuridan

Calewaert

et al. 2014

International Journal of Endocrinology

View full text Add to dashboard Cite

Aim. Our aim was to evaluate the uptake of our current screening strategy postpartum and the risk factors for glucose intolerance in women with a recent history of gestational diabetes (GDM). Methods. Retrospective analysis of files of women with a recent history of GDM diagnosed with the Carpenter and Coustan criteria from 01-01-2010 till 31-12-2013. Multivariable logistic regression was used to adjust for confounders. Results. Of all 231 women with a recent history of GDM, 21.4% (46) did not attend the scheduled postpartum OGTT. Of the women tested, 39.1% (66) had glucose intolerance and 5.3% (9) had diabetes. These women were more often overweight (39.7% versus 25.3%, P = 0.009), were more often treated with basal-bolus insulin injections (52.0% versus 17.4%, P = 0.032), and had a lower beta-cell function and lower insulin sensitivity, remaining significant after adjustment for age, BMI, and ethnicity (insulin secretion sensitivity index-2 (ISSI-2) in pregnancy 1.5 ± 0.5 versus 1.7 ± 0.4, P = 0.029; ISSI-2 postpartum 1.5 (1.2–1.9) versus 2.2 (1.8–2.6), P = 0.020; Matsuda index postpartum 3.8 (2.6–6.2) versus 6.0 (4.3–8.8), P = 0.021). Conclusion. Glucose intolerance is frequent in early postpartum and these women have a lower beta-cell function and lower insulin sensitivity. One fifth of women did not attend the scheduled OGTT postpartum.

show abstract

“…Bebek kız ise, gebelik sırasında maternal hiperglisemiye maruziyet onun da kendi gebeliklerinde GDM gelişmesi riskini artırır. Gebelik sırasındaki bu metabolik programlama tüm dünyada hızlı bir artış gösteren tip 2 DM prevalansı üzerine kuşaklar arası bir etki oluşturuyor olabilir (29).…”

Section: Fetal Ve Maternal Etki̇leri̇unclassified

Gestational diabetes mellitus

Öztürk¹

2015

Sisli Etfal

View full text Add to dashboard Cite

Abnormal fetal growth is associated with gestational diabetes mellitus later in life: population‐based register study

Abstract: Intrauterine conditions and/or genetic disposition, which affect prenatal growth, increase the future risk of the female fetus developing GDM.

Cited by 35 publications

References 22 publications

Pregnancy complications among women born preterm

Pregnancy complications among women born preterm

Glucose Intolerance after a Recent History of Gestational Diabetes

Gestational diabetes mellitus

Contact Info

Product

Resources

About