Abnormal Electrocardiographic Findings in the Population Older Than 40 Years. Prevalence and Clinical Significance. Results of the OFRECE Study

Garcia, P Awamleh; Martin, J J Alonso; Hernández, Rosa María Jiménez; Abad, Catherine Graupner; Calle, Pedro Talavera; Antolín, José Serrano; Varela, Carmen Cristóbal; Ruigómez, Alejandro Curcio; Muñiz, Javier; Doblas, Juan José Gómez; Roig, Eulàlia

doi:10.1016/j.rec.2019.01.001

Cited by 5 publications

(6 citation statements)

References 12 publications

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“…Among the whole group of study participants, the odds of ECG abnormality among people with hypertension was 3.48 times (AOR = 3.48, 95% CI = 2.02–6.37) higher than among those without hypertension. This finding was consistent with the result of previous studies from Spain, 36 Caucasian population, 9 and Angola. 15 Hypertension could be associated with ECG abnormality due to functional or structural changes.…”

Section: Discussionsupporting

confidence: 94%

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Electrocardiogram Abnormalities and Associated Factors Among People with and without Epilepsy Attending the Outpatient Department at Referral Hospitals in Amhara Regional State, Northern Ethiopia, 2022: Institutional-Based Comparative Cross-Sectional Study

Adane,

Melese,

Tesfaye

et al. 2023

NDT

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Background Epilepsy is a brain disease that is associated with electrocardiographic (ECG) abnormalities. However, this evidence is limited in Ethiopia. Studying ECG abnormality in epileptic patients could help minimize the cardiac problems and death of epileptic patients by early screening. This study was aimed to assess electrocardiogram abnormalities and associated factors among people with and without epilepsy at referral hospitals in Amhara Regional State (ARS), northern Ethiopia, 2022. Methods Institutional-based comparative cross-sectional study was conducted from April 20 to June 20, 2022. Three referral hospitals in ARS were selected by simple random sampling. Epileptic patients were selected by systematic random sampling, and 403 age- and sex-matched participants were selected from attendants of patients in the outpatient department. Interviewer-administered questionnaire and digital electrocardiograph were used for data collection. Data were entered to EpiData version 4.6 and exported to stata version 14 for analysis. Variables with P value <0.25 in bivariable analysis were entered to multivariable binary logistic regression. Strength of association was determined by adjusted odds ratio with a 95% confidence interval (CI). Results The prevalence of ECG abnormality was 40.0% (95% CI = 34.7–46.8) and 29.0% (95% CI = 23.2–34.3) in epileptic and non-epileptic subjects, respectively. The odds of ECG abnormality was 58% higher among epileptic patients. Divorce, duration of epilepsy, uncontrolled epilepsy, former/current smoker, adequate physical activity, hypertension, and overweight/obesity were associated with ECG abnormality among epileptic patients. Conclusion and Recommendations The proportion of ECG abnormality was higher among the epileptic than the non-epileptic group. This should be a wake-up call for stakeholders to establish appropriate measurements to reduce cardiac issues of epileptic patients.

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Section: Discussionsupporting

confidence: 94%

“… 8 The proportion with abnormal Q wave in this study was 5.7%. This result is higher than the studies from Spain (3.5%), 36 China (1.28%), 35 and Angola (0.71%). 15 This may be because half of the study participants in the current study were epileptic patients which may raise the proportion of Q wave abnormality.…”

Section: Discussioncontrasting

confidence: 65%

Electrocardiogram Abnormalities and Associated Factors Among People with and without Epilepsy Attending the Outpatient Department at Referral Hospitals in Amhara Regional State, Northern Ethiopia, 2022: Institutional-Based Comparative Cross-Sectional Study

Adane,

Melese,

Tesfaye

et al. 2023

NDT

View full text Add to dashboard Cite

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“…The prevalence of PR-interval prolongation ranged between 1.9% (sex-pooled 95% CI, 1.3%–3.0%) and 3.7% (95% CI, 3.1%–4.3%) in population-based studies conducted in different European countries. 3–5…”

Section: Disorders Of Atrioventricular Conductionmentioning

confidence: 99%

Heart Disease and Stroke Statistics—2022 Update: A Report From the American Heart Association

Tsao¹,

Aday²,

Almarzooq³

et al. 2022

Circulation

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2,336

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Background: The American Heart Association, in conjunction with the National Institutes of Health, annually reports the most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, diet, and weight) and health factors (cholesterol, blood pressure, and glucose control) that contribute to cardiovascular health. The Statistical Update presents the latest data on a range of major clinical heart and circulatory disease conditions (including stroke, congenital heart disease, rhythm disorders, subclinical atherosclerosis, coronary heart disease, heart failure, valvular disease, venous disease, and peripheral artery disease) and the associated outcomes (including quality of care, procedures, and economic costs). Methods: The American Heart Association, through its Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States to provide the most current information available in the annual Statistical Update. The 2022 Statistical Update is the product of a full year’s worth of effort by dedicated volunteer clinicians and scientists, committed government professionals, and American Heart Association staff members. This year’s edition includes data on the monitoring and benefits of cardiovascular health in the population and an enhanced focus on social determinants of health, adverse pregnancy outcomes, vascular contributions to brain health, and the global burden of cardiovascular disease and healthy life expectancy. Results: Each of the chapters in the Statistical Update focuses on a different topic related to heart disease and stroke statistics. Conclusions: The Statistical Update represents a critical resource for the lay public, policymakers, media professionals, clinicians, health care administrators, researchers, health advocates, and others seeking the best available data on these factors and conditions.

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Section: Discussionunclassified

“…Right bundle branch block has been linked to various comorbidities, including pulmonary hypertension, chronic obstructive pulmonary disease, hypertension, and diabetes. [21][22][23] In our population of patients with indications for pacemaker placement, RBBB may signify a more compromised overall clinical condition rather than a cardiac disease signal. Patients with baseline RBBB tended to be older, more frequently male, with chronic kidney disease, but less frequently had a history of atrial fibrillation compared with patients without conduction blocks.…”

Section: Right Bundle Branch Block and Prognosismentioning

confidence: 99%

Clinical significance and prognostic value of right bundle branch block in permanent pacemaker patients

Mazza,

Bendini,

Leggio

et al. 2024

Journal of Cardiovascular Medicine

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Aims In patients undergoing pacemaker implantation with no prior history of heart failure (HF), the presence of left bundle branch block (LBBB) has been identified as an independent predictor of HF-related death or hospitalization, while the prognostic significance of right bundle branch block (RBBB) remains uncertain. We aimed to assess the long-term risk of all-cause mortality in patients with a standard indication for permanent pacing and normal or moderately depressed left ventricular function when RBBB is detected at the time of implantation. Methods We retrospectively enrolled 1348 consecutive patients who had undergone single- or dual-chamber pacemaker implantation at the study center, from January 1990 to December 2022. Patients with a left ventricular ejection fraction ≤35% or a prior diagnosis of HF were excluded. Results The baseline 12-lead electrocardiogram revealed an RBBB in 241 (18%) and an LBBB in 98 (7%) patients. During a median follow-up of 65 [25th–75th percentile: 32–117] months, 704 (52%) patients died. The combined endpoint of cardiovascular death or HF hospitalization was reached by 173 (13%) patients. On multivariate analysis, RBBB was confirmed as an independent predictor of death [hazard ratio, 1.33; 95% confidence interval (CI), 1.09–1.63; P = 0.005]. However, when considering the combined endpoint of cardiovascular death and HF hospitalization, this endpoint was independently associated with LBBB (hazard ratio, 2.13; 95% CI, 1.38–3.29; P < 0.001), but not with RBBB. Conclusion In patients with standard pacemaker indications and normal or moderately depressed left ventricular function, the presence of basal RBBB was an independent predictor of mortality. However, it was not associated with the combined endpoint of cardiovascular death and HF hospitalization.

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Abnormal Electrocardiographic Findings in the Population Older Than 40 Years. Prevalence and Clinical Significance. Results of the OFRECE Study

Cited by 5 publications

References 12 publications

Electrocardiogram Abnormalities and Associated Factors Among People with and without Epilepsy Attending the Outpatient Department at Referral Hospitals in Amhara Regional State, Northern Ethiopia, 2022: Institutional-Based Comparative Cross-Sectional Study

Electrocardiogram Abnormalities and Associated Factors Among People with and without Epilepsy Attending the Outpatient Department at Referral Hospitals in Amhara Regional State, Northern Ethiopia, 2022: Institutional-Based Comparative Cross-Sectional Study

Heart Disease and Stroke Statistics—2022 Update: A Report From the American Heart Association

Clinical significance and prognostic value of right bundle branch block in permanent pacemaker patients

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