Abnormal dental follicle cells: A crucial determinant in tooth eruption disorders (Review)
Jiahao Chen,
Ying Ying,
Huimin Li
et al.
Abstract:The dental follicle (DF) plays an indispensable role in tooth eruption by regulating bone remodeling through their influence on osteoblast and osteoclast activity. The process of tooth eruption involves a series of intricate regulatory mechanisms and signaling pathways. Disruption of the parathyroid hormone-related protein (PTHrP) in the PTHrP-PTHrP receptor signaling pathway inhibits osteoclast differentiation by DF cells (DFCs), thus resulting in obstructed tooth eruption. Furthermore, parathyroid hormone re… Show more
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