Abnormal amplitude low-frequency oscillations in medication-naive, first-episode patients with major depressive disorder: A resting-state fMRI study

Liu, Feng; Guo, Wenbin; Liu, Ling; Long, Zhiliang; Ma, Chaoqiong; Zhang, Xue; Wang, Yifeng; Li, Jun; Hu, Maorong; Zhang, Jianwei; Du, Handan; Zeng, Lingsen; Liu, Zhening; Wooderson, Sarah C.; Tan, Chongqing; Zhao, Jingping; Chen, Huafu

doi:10.1016/j.jad.2012.10.001

Cited by 228 publications

(142 citation statements)

References 41 publications

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“…Previous studies have shown that fALFF and RSFC reflect neuronal signals and are behaviorally relevant (Biswal, 2012;Fox and Raichle, 2007;Raichle, 2010). Both aspects have been found to identify populations with various types of neuropsychiatric disorders such as attention-deficit hyperactivity disorder (ADHD; Li et al, 2014), Alzheimer's disease (Liu et al, 2008), major depressive disorder (Jiao et al, 2011;Wang et al, 2012;Liu et al, 2013), mild cognitive impairment (Han et al, 2011;Zhao et al, 2014), and schizophrenia (Hoptman et al, 2010;Yu et al, 2014). In addition, several recent studies have shown healthy individuals' fALFF and RSFC are associated with individual differences in executive control (Mennes et al, 2011;Xu et al, 2014), face processing (Zhu, Zhang, Luo, Dilks, & Liu, 2011), object color processing (Wang et al, 2013), emotional intelligence (Cox et al, 2012;Takeuchi et al, 2013), and personality traits .…”

Section: Introductionmentioning

confidence: 99%

Different neural pathways linking personality traits and eudaimonic well-being: a resting-state functional magnetic resonance imaging study

Kong

Liu

Wang

et al. 2014

Cogn Affect Behav Neurosci

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Eudaimonic well-being (EWB) is the fulfillment of human potential and a meaningful life. Previous studies have shown that personality traits, especially extraversion, neuroticism, and conscientiousness, significantly contribute to EWB. However, the neurobiological pathways linking personality and EWB are not understood. Here, we used restingstate functional magnetic resonance imaging (rs-fMRI) to investigate this issue. Specifically, we correlated individuals' EWB scores with the regional fractional amplitude of lowfrequency fluctuations (fALFF) of the brain, and then examined how personality traits predicted EWB-related spontaneous brain activity. We found that EWB was positively correlated with the fALFF in the right posterior superior temporal gyrus (pSTG) and thalamus, and negatively correlated with the strength of the thalamic-insular connectivity. More importantly, we found that personality traits influenced EWB in different ways. At the regional level, the fALFF in the pSTG and thalamus mediated the effects of neuroticism and extraversion on EWB, whereas the thalamus mediated the effect of conscientiousness on EWB. At the functional connectivity level, the thalamic-insular connectivity only mediated the effect of neuroticism on EWB. Taken together, our study provides the first evidence that EWB is associated with personality traits through different neural substrates.

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Section: Introductionmentioning

confidence: 99%

Different neural pathways linking personality traits and eudaimonic well-being: a resting-state functional magnetic resonance imaging study

Kong

Liu

Wang

et al. 2014

Cogn Affect Behav Neurosci

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“…Most previous neuroimaging studies have identified altered GMV [41,42], decreased surface area [43], reduced voxel-mirrored homotopic connectivity [44], and increased fractional amplitude of low-frequency fluctuations [45] in the left CUN in MDD patients. Moreover, the GMV in the CUN was also reported to be associated with better inhibitory control in bipolar depression patients [46].…”

Section: Discussionmentioning

confidence: 97%

“…Although the Cereb has long been recognized as a region which coordinates motor behavior [31], most imaging studies reported that it was involved in working memory [32,33], showing significant activation in the cerebellar posterior lobe during the working memory paradigms. Moreover, numerous neuroimaging studies have shown structural [34] or functional abnormalities [35,36] of the Cereb in MDD patients. Given the important roles of the left Fp1, left FG and right Cereb in memory, the decreased RSFC between left Fp1 and left FG, right Cereb in the MDD patients after ECT may be associated with the memory deficits after ECT.…”

Section: Discussionmentioning

confidence: 99%

Electroconvulsive Therapy Modulates the Structural and Functional Architecture of Frontal Pole in Major Depressive Disorder

Xu¹,

Wang²,

Xu³

et al. 2018

Neuropsychiatry

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“…Briefly, the first step was to discard the 10 initial scans of all experiment runs, because of magnetic equilibration effects and participants adapting to the scanning noise [19]. Second, the remaining images were corrected for the acquisition time delay between slices.…”

Section: Data Preprocessing and The Whole Brain Functionalmentioning

confidence: 99%

Amygdala-Prefrontal Connectivity Analysis of Decoding Human Emotion

We¹,

Bu²,

Li³

et al. 2017

Proceedings of the 2016 International Conference on Biological Engineering and Pharmacy (BEP 2016)

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Abstract-Functional neuroimaging studies have found that emotion network in patients with some psychiatric and neurological diseases was abnormal. However, human emotion network is extremely complex and understanding of it still remains unclear. So, it's difficult to regulate and remodel emotion network directly. Here, we first estimated the critical connectivity from whole brain functional connectivity, whose seed regions were the structurally and functionally distinct nuclei of amygdala, the basolateral amygdala (BLA) and centromedial amygdala (CMA). And then the critical connectivity was extracted from whole brain functional connectivity using a machine learning method. The experimental results showed that the connectivity between left amygdala and various regions of the prefrontal gyrus, especially right medial superior frontal gyrus, performed better in the classification. Moreover, real time fMRI neurofeedback training also demonstrated that the critical connectivity provided a great contribution for emotion regulation. These findings may be useful support for the connectivity-based emotion regulation training and possibly applied to supplementary treatment of emotion illness.

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Abnormal amplitude low-frequency oscillations in medication-naive, first-episode patients with major depressive disorder: A resting-state fMRI study

Cited by 228 publications

References 41 publications

Different neural pathways linking personality traits and eudaimonic well-being: a resting-state functional magnetic resonance imaging study

Different neural pathways linking personality traits and eudaimonic well-being: a resting-state functional magnetic resonance imaging study

Electroconvulsive Therapy Modulates the Structural and Functional Architecture of Frontal Pole in Major Depressive Disorder

Amygdala-Prefrontal Connectivity Analysis of Decoding Human Emotion

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