Abnormal, abusive, and stress-related behaviors in baboon mothers

Brent, Linda; Koban, Tina; Ramirez, Stephanie M.

doi:10.1016/s0006-3223(02)01540-8

Cited by 38 publications

(28 citation statements)

References 60 publications

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“…The maternalmediation hypothesis therefore predicts that IS infants will consistently receive more maternal care than NS infants. Although it is unknown whether MIS infants develop stress resistance, this condition was included because maternal stress diminishes primate maternal care (21). If MIS infants receive less or equal amounts of maternal care compared with control infants, the maternal mediation hypothesis predicts that MIS infants will not develop neuroendocrine stress resistance.…”

Section: Methodsmentioning

confidence: 99%

Maternal mediation, stress inoculation, and the development of neuroendocrine stress resistance in primates

Parker

Buckmaster

Sundlass

et al. 2006

Proc. Natl. Acad. Sci. U.S.A.

184

152

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The stress inoculation hypothesis presupposes that brief intermittent stress exposure early in life induces the development of subsequent stress resistance in human and nonhuman primates. Rodent studies, however, suggest a role for maternal care rather than stress exposure per se (i.e., the maternal mediation hypothesis). To investigate these two hypotheses, we examined maternal care and the development of stress resistance after exposure to brief intermittent infant stress (IS), mother-infant stress (MIS), or no stress (NS) protocols administered to 30 monkeys between postnatal weeks 17 and 27. Unlike rodents, the IS condition did not permanently increase primate maternal care, nor did measures of total maternal care predict subsequent offspring hypothalamicpituitary-adrenal-axis responsivity. Although MIS infants received less maternal care than IS and NS infants, both IS and MIS monkeys developed subsequent stress resistance. These findings indicate that rearing differences in the development of stress resistance are more closely related to differences in prior stress exposure than to differences in maternal care. A second experiment confirmed this conclusion in a different cohort of 25 monkeys exposed as infants to high foraging-demand (HFD) or low foraging-demand (LFD) conditions. HFD infants exhibited intermittent elevations in cortisol levels and received less maternal care than LFD infants. In keeping with a key prediction of the stress inoculation hypothesis, HFD males responded to stress in adulthood with diminished hypothalamic-pituitary-adrenal-axis activation compared with LFD males. Results from both experiments demonstrate that stress inoculation, rather than high levels of maternal care, promotes the development of primate stress resistance.hypothalamic-pituitary-adrenal axis ͉ monkey ͉ maternal care ͉ resilience

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Section: Methodsmentioning

confidence: 99%

Maternal mediation, stress inoculation, and the development of neuroendocrine stress resistance in primates

Parker

Buckmaster

Sundlass

et al. 2006

Proc. Natl. Acad. Sci. U.S.A.

184

152

View full text Add to dashboard Cite

show abstract

“…Treatment with an oestrogen receptor-β agonist was able to alleviate the depressive symptoms [205,206]. Furthermore, it could be shown in different non-human primate species that stress induced increases in plasma cortisol concentrations and that this rise was associated with abnormal maternal behaviour, like infant neglect [207,208]. In a recent study by Saltzman and Abbott [178], it could be shown that exogenous administration of cortisol to lactating female marmosets impaired maternal motivation and interfered with the expression of appropriate maternal behaviour.…”

Section: Consequences Of Chronic Stress In Pregnancy On Behavioural Pmentioning

confidence: 99%

From Stress to Postpartum Mood and Anxiety Disorders: How Chronic Peripartum Stress Can Impair Maternal Adaptations

Hillerer¹,

Neumann²,

Slattery³

2011

Neuroendocrinology

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The peripartum period, in all mammalian species, is characterised by numerous adaptations at neuroendocrine, molecular and behavioural levels that prepare the female for the challenges of motherhood. These changes have been well characterised and, while they are necessary to ensure the survival and nurturance of the offspring, there is growing belief that they are also required for maternal mental health. Thus, while increased calmness and attenuated stress responsivity are common characteristics of the peripartum period, it also represents a time of increased susceptibility to mood disorders. While a number of risk factors for these disorders are known, their underlying aetiology remains poorly understood, due at least in part to a lack of appropriate animal models. One translatable risk factor is stress exposure during the peripartum period. In the following review we first describe common peripartum adaptations and the impact postpartum mood disorders have on these. We then discuss the known consequences of peripartum stress exposure on such maternal adaptations that have been described in basic research.

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“…single offspring) and developmental timing. Infant maltreatment has been documented in both wild and captive populations of NHP species (Brent and Koban, 2002; Johnson et al, 1996; Maestripieri, 1998; Maestripieri and Carroll, 1998). In macaques, often during the first three months postpartum, two behaviors resembling child maltreatment occur that result in overt signs of infant distress (screams, tantrums): (1) physical abuse, which involves violent behaviors toward the infant that cause pain and distress (e.g.…”

Section: Conceptual and Definitional Challenges For Cross-species Commentioning

confidence: 99%

When mothering goes awry: Challenges and opportunities for utilizing evidence across rodent, nonhuman primate and human studies to better define the biological consequences of negative early caregiving

Drury

Sánchez

González

2016

Hormones and Behavior

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Across mammalian species, mothers shape socio-emotional development and serve as essential external regulators of infant physiology, brain development, behavior patterns, and emotional regulation. Caregiving quality, consistency and predictability shape the infant's underlying neurobiological processes. Although the requirements for “optimal” caregiving differ across species, the negative long-term consequences of the absence of needed caregiving (e.g. neglect) or the presence of harmful/aversive caregiving (e.g. physical abuse), are translatable across species. Recognizing the significant potential of cross species comparisons in terms of defining underlying mechanisms, effective translation requires consideration of the evolutionary, ecological, and fundamental biological and developmental differences between and among species. This review provides both an overview of several success stories of cross-species translations in relation to negative caregiving and a template for future studies seeking to most effectively define the underlying biological processes and advance research dedicated to mitigating the lasting negative health consequences of child maltreatment.

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Abnormal, abusive, and stress-related behaviors in baboon mothers

Cited by 38 publications

References 60 publications

Maternal mediation, stress inoculation, and the development of neuroendocrine stress resistance in primates

Maternal mediation, stress inoculation, and the development of neuroendocrine stress resistance in primates

From Stress to Postpartum Mood and Anxiety Disorders: How Chronic Peripartum Stress Can Impair Maternal Adaptations

When mothering goes awry: Challenges and opportunities for utilizing evidence across rodent, nonhuman primate and human studies to better define the biological consequences of negative early caregiving

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