Ablação com radiofreqüência de extra-sístoles da via de saída do ventrículo direito

Darrieux, Francisco; Scanavacca, Maurício; Hachul, Denise Tessariol; Melo, Sissy Lara de; D'Ávilla, André B; Gruppi, C; Moffa, Paulo Jorge; Sosa, Eduardo

doi:10.1590/s0066-782x2007000300003

Cited by 19 publications

(13 citation statements)

References 22 publications

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“…Our current results indicate a significant improvement in PVC of the outflow tract. Right ventricular outflow tract is the most common origin of PVC in patients without structural heart disease 29 . That site might have remnant cells of the neural crest and of adrenergic modulation.…”

Section: Discussionmentioning

confidence: 99%

Late Outcome of a Randomized Study on Oral Magnesium for Premature Complexes

Falco

Darrieux

Grupi

et al. 2014

Arquivos Brasileiros De Cardiologia

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BackgroundVentricular and supraventricular premature complexes (PC) are frequent and usually symptomatic. According to a previous study, magnesium pidolate (MgP) administration to symptomatic patients can improve the PC density and symptoms.ObjectiveTo assess the late follow-up of that clinical intervention in patients treated with MgP or placebo.MethodsIn the first phase of the study, 90 symptomatic and consecutive patients with PC were randomized (double-blind) to receive either MgP or placebo for 30 days. Monthly follow-up visits were conducted for 15 months to assess symptoms and control electrolytes. 24-hour Holter was performed twice, regardless of symptoms, or whenever symptoms were present. In the second phase of the study, relapsing patients, who had received MgP or placebo (crossing-over) in the first phase, were treated with MgP according to the same protocol.ResultsOf the 45 patients initially treated with MgP, 17 (37.8%) relapsed during the 15-month follow-up, and the relapse time varied. Relapsing patients treated again had a statistically significant reduction in the PC density of 138.25/hour (p < 0.001). The crossing-over patients reduced it by 247/hour (p < 0.001). Patients who did not relapse, had a low PC frequency (3 PC/hour). Retreated patients had a 76.5% improvement in symptom, and crossing-over patients, 71.4%.ConclusionSome patients on MgP had relapse of symptoms and PC, indicating that MgP is neither a definitive nor a curative treatment for late follow-up. However, improvement in the PC frequency and symptoms was observed in the second phase of treatment, similar to the response in the first phase of treatment.

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Section: Discussionmentioning

confidence: 99%

Late Outcome of a Randomized Study on Oral Magnesium for Premature Complexes

Falco

Darrieux

Grupi

et al. 2014

Arquivos Brasileiros De Cardiologia

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“…The aim of the treatment is therefore to reduce symptoms and improve quality of life [3] . Radiofrequency ablation (RFA) is a safe and effective treatment to reduce symptoms and eliminate VT and PVCs [4] . As many of the patients are young and healthy individuals, a single intervention with RFA may be preferred over the lifelong use of antiarrhythmic drugs.…”

Section: Introductionmentioning

confidence: 99%

10-year follow-up after radiofrequency ablation of idiopathic ventricular arrhythmias from right ventricular outflow tract

Rørvik

Chen

Hoff

et al. 2016

Indian Pacing and Electrophysiology Journal

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BackgroundThe aim of this study was to examine the effect of radiofrequency ablation (RFA) of ventricular arrhythmias from right ventricular outflow tract (RVOT) during long-term follow-up.MethodsA follow-up analysis was conducted using an in-house questionnaire, as well as a qualitative assessment of the patients' medical records. The study population of 34 patients had a previous diagnosis of idiopathic VT or frequent PVCs from the RVOT, and received RFA treatment between 2002 and 2005.ResultsThe main symptoms prior to RFA were palpitations (82.4%) and dizziness (76.5%). A reduction in symptoms following RFA was reported by 91.2% of patients (p < 0.001). Furthermore, there was a reduced use of antiarrhythmic medication after RFA (p < 0.001). General health perception classified on a scale of 1 (poor) to 4 (excellent), improved from median class 1 to 3 (p < 0.001) during long-term follow-up. The fitness to work increased from median class 3 to class 5 (1 = incapacitated, 5 = full time employment, p = 0.038), while the rate of patients in full time employment increased from 26.5% to 55.9% after RFA (p = 0.02).ConclusionsA reduction of symptoms and use of antiarrhythmic medication, as well as an improvement in the general health perception and fitness to work after RFA of idiopathic ventricular arrhythmias can be demonstrated at ten-year follow-up.

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“…A nonirrigated ablation catheter has been used for treatment of these types of arrhythmias,[ 5 ] and the success rate has been reported to be between 80% and 92%,[ 9 10 ] the recurrence rate is high (10%–24%) during follow-up. [ 10 11 ] The underlying reasons for failed ablation are not yet fully clarified, but one reason might be unpredictable power delivery because of variations in endocardial contact.…”

Section: Introductionmentioning

confidence: 99%

Adenosine Sensitivity is Associated with Ablation Success Rate and Recurrence Rate with Nonirrigated Catheters in Patients with Ventricular Premature Contractions/Tachycardia from the Ventricular Outflow Tract

Feng

Wang

Sun

et al. 2015

Chinese Medical Journal

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Background:A high ablation success rate for ventricular arrhythmia (VA) from outflow tract has been achieved, but some of them cannot be eliminated from endocardium. We investigated the association between adenosine sensitivity and ablation success/recurrence rates with a nonirrigated or an irrigated catheter.Methods:According to adenosine test, all patients were divided into a sensitive group (S group) or an insensitive group (I group). The patients of each group were randomized into a nonirrigated catheter (NA) subgroup or an irrigated catheter (IA) subgroup with a 2:1 ratio.Results:In S group of 122 patients (84 in NA subgroup), the ablation success rate was similar between two subgroups (94.7% vs. 90.5%, P > 0.05), but in I group of 94 patients (60 in NA subgroup), it was higher in IA subgroup (94.1%) than that in NA subgroup (73.3%, P < 0.05). The success rate using nonirrigated catheter was significantly higher in S group (90.5%) than that in I group (73.3%, P < 0.01), and the recurrence rate was lower in S group than that in I group (1.3%, vs. 13.6%, P < 0.05). On the contrary, the success rate and the recurrence rate using irrigated catheter were similar between S group and I group (94.7%, 94.1%, P > 0.05, vs. 2.8%, 6.3%, P > 0.05).Conclusions:Adenosine insensitivity is associated with a lower success rate and a higher recurrence rate for VA patients undergoing nonirrigated catheter ablation. Thus, irrigated catheters should be the first choice for VA ablation in adenosine insensitive patients.

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Ablação com radiofreqüência de extra-sístoles da via de saída do ventrículo direito

Cited by 19 publications

References 22 publications

Late Outcome of a Randomized Study on Oral Magnesium for Premature Complexes

Late Outcome of a Randomized Study on Oral Magnesium for Premature Complexes

10-year follow-up after radiofrequency ablation of idiopathic ventricular arrhythmias from right ventricular outflow tract

Adenosine Sensitivity is Associated with Ablation Success Rate and Recurrence Rate with Nonirrigated Catheters in Patients with Ventricular Premature Contractions/Tachycardia from the Ventricular Outflow Tract

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