Ability to perform activities of daily living among patients with bipolar disorder in remission

Abstract

Aims: Patients with bipolar disorder often experience disability in terms of cognitive impairments and activity limitations even in remission. However, knowledge is sparse concerning the ability to perform Activities of Daily Living (ADL) during remission. The aim of this study was to (1) investigate the observed and self-reported ability to perform ADL tasks and (2) examine the association between observed and self-reported ability to perform ADL in patients with bipolar disorder in remission. Methods: The observed ADL ability was assessed with the Assessment of Motor and Process Skills, a standardized assessment providing interpretation of ADL ability in relation to competence, independence, and normative age expectations. Self-reported ADL ability was assessed with the standardized ADL-Questionnaire. Results: Forty-three patients with bipolar disorder in remission (median age 35 years, range 19–58 years) were assessed and overall, they displayed decreased observed ADL motor and ADL process ability relative to normative age. They exhibited increased physical effort, clumsiness or fatigue and/or inefficiency, there was concern for safe task performance and one-third may need assistance to live in the community. While participants reported decreased ADL ability, especially within instrumental ADL, they had a tendency towards evaluating themselves as more competent than what was observed. No relationships between measures of observed and self-reported ADL ability were found. Conclusion: Overall, patients with bipolar disorder in remission showed decreased ability to perform ADL. Clinical practice and future studies are recommended to use both observation-based and self-reported assessments of the ability to perform ADL tasks to fully capture disability in bipolar disorder.

Echocardiographic evaluation of myocardial strain in bipolar disorder across different phases: A comparative study with healthy controls

“…Myocardial deformation, a parameter that provides information on cardiac muscle deformation during the cardiac cycle, is an important indicator of myocardial function and has been associated with various cardiac pathologies. [4]…”

“…Myocardial deformation, a parameter that provides information on cardiac muscle deformation during the cardiac cycle, is an important indicator of myocardial function and has been associated with various cardiac pathologies. [4] The primary objective of this study is to fill this research gap by investigating myocardial strain patterns in patients diagnosed with bipolar disorder during different phases of their illness compared to healthy controls. This objective is driven by the hypothesis that bipolar disorder, with its varying emotional and physiological stresses in different phases, may have distinct impacts on cardiac function.…”