Ability of Latin America laboratories to detect antimicrobial resistance patterns: experience of the SENTRY antimicrobial surveillance program (1997-2000)

Mendes, Rodrigo E.; Reis, Adriana Oliver; Gales, Ana Cristina; Jones, Ronald N.; Sader, Hélio S.

doi:10.1590/s1413-86702003000500001

Cited by 7 publications

(5 citation statements)

References 13 publications

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“…However, the most appropriate choice of extended-spectrum cephalosporins and type of confirmatory test that provides the greatest assay sensitivity have yet to be determined. For instance, in early testing, the E-test ESBL screen test with ceftazidime or cefepime as substrate, and use of Oxoid combination discs with cefotaxime and ceftazidime, were useful for demonstrating the presence of Enterobacteriaceae potentially producing ESBLs but were also associated with clinically significant false-susceptible and false-resistant results [51, 52]. Current guidance from the Clinical and Laboratory Standards Institute (CLSI) describes laboratory detection of ESBL produced by E. coli, P. mirabilis , and Klebsiella spp., but not for species with inducible AmpC β -lactamases (such as Enterobacter spp.)…”

Section: Surveillance and Detectionmentioning

confidence: 99%

Resistant Gram-negative infections in the outpatient setting in Latin America

et al. 2013

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SUMMARYLatin America has a high rate of community-associated infections caused by multidrug-resistant Enterobacteriaceae relative to other world regions. A review of the literature over the last 10 years indicates that urinary tract infections (UTIs) by Escherichia coli, and intra-abdominal infections (IAIs) by E. coli and Klebsiella pneumoniae, were characterized by high rates of resistance to trimethoprim/sulfamethoxazole, quinolones, and second-generation cephalosporins, and by low levels of resistance to aminoglycosides, nitrofurantoin, and fosfomycin. In addition, preliminary data indicate an increase in IAIs by Enterobacteriaceae producing extended-spectrum β-lactamases, with reduced susceptibilities to third- and fourth-generation cephalosporins. Primary-care physicians in Latin America should recognize the public health threat associated with UTIs and IAIs by resistant Gram-negative bacteria. As the number of therapeutic options become limited, we recommend that antimicrobial prescribing be guided by infection severity, established patient risk factors for multidrug-resistant infections, acquaintance with local antimicrobial susceptibility data, and culture collection.

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Section: Surveillance and Detectionmentioning

confidence: 99%

Resistant Gram-negative infections in the outpatient setting in Latin America

et al. 2013

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“…The Clinical and Laboratory Standard Institute (CLSI) standardized the disk diffusion method for cefoxitin as a presumptive method of the mecA gene, but the phenotypic expression of this gene is still a challenge for microbiology laboratories (2,3,9,24,28) due to the discrepancies observed between laboratories that participate in the Antimicrobial Surveillance Program (23) . Currently, one of the main objectives for the control of hospital infections is the rational use of antimicrobials, which makes the evaluation of the accuracy of phenotypic methods used for determining the susceptibility profile essential for guaranteeing the most appropriate choice of therapeutic antimicrobials (19) .…”

Section: Introductionmentioning

confidence: 99%

Phenotypic methods for determination of methicillin resistance in Staphylococcus spp. from health care workers

Rabelo¹,

Neto²,

Silva³

et al. 2013

J. Bras. Patol. Med. Lab.

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“…Quality control of laboratory procedures through a regional referral center is highly desired. 8 At present, the northern area of Lima should be considered a high-risk area for ORSA and MDRSA infection.…”

Section: Discussionmentioning

confidence: 99%