Aberrant Right Subclavian Artery

Simultaneous occurrence of an aberrant right subclavian artery and accessory lobe of the liver

“…The ARSA found in this study accompanied known, clinically significant, anomalies: Kommerell's diverticulum seemed to press the esophagus, the right-sided thoracic duct emptied into the right angulus venosus, and there was a nonrecurrent right laryngeal nerve (Raider 1967). In addition to these anomalies, in the abdominal cavity, the liver had an accessory lobe that protruded from the anterior margin of the left liver lobe.…”

Fetal Aberrant Right Subclavian Artery (ARSA) – a Potential New Soft Marker in the Genetic Scan?

“…Prenatal studies using an ARSA as a new soft marker to detect fetuses with Down syndrome are sparse [7 -10]. The prevalence of ARSA, as the most common congenital aortic arch anomaly, was 1.05% in our study, which is in the upper range of the reported incidence in the general postnatal population (0.5 -1.0%) [3,5,6], but compares well with the prenatal data of Chaoui et al [8] and Zalel et al [9], who reported that an ARSA was found in 1.4% of healthy fetuses. In a preliminary study of 14 fetuses with Down syndrome, Chaoui et al found an aberrant right subclavian artery in 37.5% of cases [8].…”

“…dition with a left aortic arch (LAA) and ARSA, the right aortic arch regresses between rather than distal to the common carotid and right subclavian artery. Therefore, the development of the brachiocephalic trunk is hindered and results in a left-sided aortic arch giving rise to four arteries (the right common carotid, the left common carotid, the left subclavian artery and the aberrant right subclavian artery) [3,4]. An aberrant right subclavian artery (ARSA) is the most common congenital aortic arch anomaly and is found in approximately 0.5 -1.0 % of the general population [3,5,6].…”

“…Therefore, the development of the brachiocephalic trunk is hindered and results in a left-sided aortic arch giving rise to four arteries (the right common carotid, the left common carotid, the left subclavian artery and the aberrant right subclavian artery) [3,4]. An aberrant right subclavian artery (ARSA) is the most common congenital aortic arch anomaly and is found in approximately 0.5 -1.0 % of the general population [3,5,6]. Recently, prenatal ultrasound studies have reported that the incidence of ARSA in the second trimester is approximately 1.4 % in healthy fetuses, but 28.6 % to 37.5 % in fetuses with Down syndrome [7 -9].…”

Aberrant right subclavian artery in Down syndrome fetuses

“…ARSA is characterized by abnormal origination of the right subclavian artery directly from descending aorta instead of the brachiocephalic trunk. Although the real prevalance is not known, data from post‐natal autopsies, catheterisation series, and from prenatal screening studies conclude that ARSA is present in 0.4–2.3% of the low‐risk population . Angiographic studies in children detected ARSA in 35% of children with trisomy 21 .…”