Aberrant Claustrum Structure in Preterm-Born Neonates: An MRI Study

Emotional Regulation Interventions on Developmental Course for Preterm Children: A Systematic Review of Randomized Control Trials

“…Then, emotion dysregulation can lead premature children to be unable to handle environmental stimuli, showing hyperactive responses and low tolerance to the slightest stimulation, putting children born prematurely at a disadvantage during social situations [ 14 , 15 , 16 ]. It has been found that several risk factors such as atypical structural maturation of the brain regions underlying social cognition could lead to developmental delays or abnormalities [ 17 , 18 , 19 ]. At age 6, reduced connectivity was found in all emotions except the response to angry faces.…”

“…The affected areas are the amygdala and the frontal regions, in particular the superior frontal gyrus and between the orbital frontal cortex and the anterior cingulate [ 20 , 21 , 22 , 23 , 24 , 25 ]. Other volumetric alterations have been found in samples of preterm infants in infancy and adolescence with changes in both white and gray matter [ 17 ]: reduced volume of the fusiform gyrus [ 26 , 27 ], thalamus [ 19 ], insula [ 26 ] and hippocampus [ 28 , 29 , 30 , 31 ]. However, different studies have identified, in addition to emotional dysregulation, an impairment of social cognitive skills related to the Theory of Mind [ 12 , 32 ].…”