Abdominal Tumors

Castle, Jennifer T.; Levy, Brittany E.; Rodeberg, David A.

doi:10.1016/j.suc.2022.07.006

Cited by 4 publications

(2 citation statements)

References 113 publications

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“…Comprehensive treatment of NB is associated with multiple complications, including cognitive deficits, cardiotoxicity, and chronic kidney disease [ 1 , 11 , 12 ]. In addition, many individual cases have reported a second tumor after treatment [ 13 , 14 ].…”

Section: Discussionmentioning

confidence: 99%

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Inflammatory myofibroblastic tumor of the liver after adrenal neuroblastoma surgery: a case report

Shen,

Liu,

Zhang

et al. 2024

Discov Onc

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A boy aged 55 months was diagnosed with stage IV Neuroblastoma (NB) of the right adrenal gland 2 years ago. Preoperative chemotherapy was given and he was then treated with retroperitoneal tumor resection and lymph node dissection. After surgery, the children were transferred to the Hemato-Oncology Department for chemotherapy according to the high-risk group NB, with outpatient follow-up every 6 months. In the second postoperative year, abdominal computed tomography (CT) scan revealed a rounded hypodense area in the upper part of the right posterior lobe of the liver, with marked inhomogeneous enhancement in the venous phase after enhancement, which was surgically resected, and postoperative pathology confirmed inflammatory myofibroblastic tumor (IMT) of liver. The patient was not given any special treatment after surgery. In this study, whole transcriptome sequencing was performed on the postoperative specimen of adrenal NB and the specimen of IMT of liver. This unusual case emphasizes the need for close monitoring of second tumor development in NB survivors even in the absence of known predisposing factors.

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Section: Discussionmentioning

confidence: 99%

“…With improved diagnostic and treatment modalities for neuroblastoma (NB), the prognosis for patients is getting better, but the risk of patients developing a second tumor remains [ 1 ]. A so-called second tumor is another tumor that develops near or away from the primary tumor [ 2 ].…”

Section: Introductionmentioning

confidence: 99%