Abdominal Masses

Potisek, Nicholas M.; Antoon, James W.

doi:10.1542/pir.2016-0087

Cited by 15 publications

(9 citation statements)

References 3 publications

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“…The liver accounts for 5-6% of all intra-abdominal masses detected in children, with renal being the most common [1]. One-third of these masses are considered to be benign, whereas two-thirds are malignant [2].…”

Section: Introductionmentioning

confidence: 99%

Pediatric Primary Hepatic Tumors: Diagnostic Considerations

2021

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The liver is the third most common site of abdominal tumors in children. This review article aims to summarize current evidence surrounding identification and diagnosis of primary hepatic tumors in the pediatric population based upon clinical presentation, epidemiology, and risk factors as well as classical imaging, histopathological, and molecular diagnostic findings. Readers will be able to recognize the features and distinguish between benign and malignant hepatic tumors within different age groups.

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Section: Introductionmentioning

confidence: 99%

Pediatric Primary Hepatic Tumors: Diagnostic Considerations

2021

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“…Malignant abdominal tumors in children represent the set of expansive malignant processes that develop in the abdominal cavity [2]. They are often discovered incidentally by a parent, during a physical examination or detected on abdominal imaging [3]. They usually present in the form of an abdominal mass or an increase in abdominal volume, or by non-specific signs: digestive and voiding disorders (by compression), arterial hypertension, hematoma, general signs (fever, weight loss), rarely a complication (acute intussusception) [2].…”

Section: Introductionmentioning

confidence: 99%

Clinico-Pathological Profile of Malignant Abdominal Tumors in Children: Experience of the Pediatric Oncology Unit in Bamako

Doumbia¹,

Dembelé²,

Togo³

et al. 2021

OJPed

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“…Abdominal masses in children can result from a number of etiologies ranging from benign conditions to malignant tumors. Most pediatric abdominal masses arise from the kidney and are benign ( 1 ). In fact, a pediatric renal mass is more likely to be hydronephrosis, or if solid, congenital mesoblastic nephroma ( 1 , 2 ).…”

Section: Introductionmentioning

confidence: 99%

“…Most pediatric abdominal masses arise from the kidney and are benign ( 1 ). In fact, a pediatric renal mass is more likely to be hydronephrosis, or if solid, congenital mesoblastic nephroma ( 1 , 2 ). Nevertheless, abdominal masses, which are often detected incidentally by the child’s caretaker, may be malignant neoplasms.…”

Section: Introductionmentioning

confidence: 99%

“…Neuroblastomas are the most common extracranial malignancy in children presenting most frequently in the adrenal glands. While relatively more rare, pediatric renal cancer makes up approximately 6% to 7% of all pediatric cancers ( 1 , 3 , 4 ) including Wilms’ tumor (WT), renal cell carcinoma (RCC), rhabdoid tumor, clear cell sarcoma, and other less frequent pathologies.…”

Section: Introductionmentioning

confidence: 99%

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Lymph node imaging of pediatric renal and suprarenal malignancies

Gold

Sabarwal

Gordhan

et al. 2018

Transl. Androl. Urol

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Pediatric renal and suprarenal cancers are relatively rare malignancies, but are not without significant consequence to both the patient and caretakers. These tumors are often found incidentally and present as large abdominal masses. Standard of care management involves surgical excision of the mass, but contemporary treatment guidelines advocate for use of neoadjuvant or adjuvant chemotherapy for advanced stage disease, such as those cases with lymph node involvement (LNI). However, LNI detection is based primarily on surgical pathology and performing extended lymph node dissection can add significant morbidity to a surgical case. In this review, we focus on the use and performance of imaging modalities to detect LNI in Wilms’ tumor (WT), neuroblastoma, and pediatric renal cell carcinoma (RCC). We report on how imaging impacts management of these cases and the clinical implications of LNI. A literature search was conducted for studies published on imaging-based detection of LNI in pediatric renal and suprarenal cancers. Further review focused on surgical and medical management of those cases with suspected LNI. Current imaging protocols assisting in diagnosis and staging of pediatric renal and suprarenal cancers are generally limited to abdominal ultrasound and cross-sectional imaging, mainly computed tomography (CT). Recent research has investigated the role of more advance modalities, such as magnetic resonance imaging (MRI) and positron emission tomography (PET), in the management of these malignancies. Special consideration must be made for pediatric patients who are more vulnerable to ionizing radiation and have characteristic imaging features different from adult controls. Management of pediatric renal and suprarenal cancers is influenced by LNI, but the rarity of these conditions has limited the volume of clinical research regarding imaging-based staging. As such, standardized criteria for LNI on imaging are lacking. Nevertheless, advanced imaging modalities are being investigated and potentially represent more accurate and safer options.

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Abdominal Masses

Cited by 15 publications

References 3 publications

Pediatric Primary Hepatic Tumors: Diagnostic Considerations

Pediatric Primary Hepatic Tumors: Diagnostic Considerations

Clinico-Pathological Profile of Malignant Abdominal Tumors in Children: Experience of the Pediatric Oncology Unit in Bamako

Lymph node imaging of pediatric renal and suprarenal malignancies

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