Abdominal Lemierre Syndrome – An Odd Presentation of a Rare Entity

Handa, Shivani; Panthagani, Anyonya; Buddhdev, Amita

doi:10.29024/jsim.64

Cited by 3 publications

(5 citation statements)

References 4 publications

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“…Pylephlebitis can become complicated and result in hepatic abscesses - abdominal Lemierre’s syndrome, bowel ischemia, and portal hypertension 3 . It can also lead to sepsis, which is usually the most common cause of mortality in these patients 6 . Finally, there may be a link between chemotherapy-related immune suppression and enhanced bacterial virulence similar to the use of non-steroidal anti-inflammatory drugs and steroids in cancer patients 7 .…”

Section: Discussionmentioning

confidence: 99%

“…As mentioned above, an abdominal Lemierre’s syndrome due to Fusobacterium is a rare occurrence. Other pathogens that cause this infection are Streptococcus viridans, Escherichia coli, and Bacteroides fragilis 6 . In most cases, patients are febrile and present with a right upper quadrant tenderness.…”

Section: Discussionmentioning

confidence: 99%

“…First, broad- spectrum antibiotics are given to the patients against the common pathogens until laboratory results prove that it is a Fusobacterium infection. Then, for Fusobacterium, third- generation cephalosporins with metronidazole or beta lactam/beta lactamase inhibitors or carbapenems are effective and should be given for four to six weeks 4 , 6 . In this case, beta lactam/beta-lactamase inhibitors treated the patient successfully.…”

Section: Discussionmentioning

confidence: 99%

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Abdominal variant of Lemierre’s Syndrome in a Patient with Pancreatic Adenocarcinoma

Furuncuoglu

Öven

Mert

et al. 2021

MMJ

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Lemierre’s syndrome is an illness characterized by internal jugular vein thrombophlebitis related to infectious agents, primarily Fusobacterium necrophorum. These bacteria, residing in both the oropharynx and the gastrointestinal tract, may lead to pylephlebitis, a serious condition that could result in the development of hepatic abscesses. This manifestation of the disease is regarded as the abdominal variant of Lemierre’s syndrome. Patients with gastrointestinal malignancies, especially those who undergo surgeries, are susceptible to the abdominal variant of Lemierre’s syndrome. Timely diagnosis is required to avoid the life-threatening complications of the abdominal variant of Lemierre’s syndrome. Diffusion-weighted magnetic resonance imaging (MRI) might be very useful in differentiating this disease from liver metastasis in patients with malignancies. Radiologists and clinicians need to be aware of this challenging condition to prevent misdiagnosis, since prompt treatment is often lifesaving.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Abdominal variant of Lemierre’s Syndrome in a Patient with Pancreatic Adenocarcinoma

Furuncuoglu

Öven

Mert

et al. 2021

MMJ

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“…The most common species isolated within this genus are F. necrophorum and F. nucleatum , the former is more commonly known to cause Lemierre's syndrome 2 . Variants of Lemierre's syndrome caused by Fusobacterium species have also been described in multiple anatomic locations such as hepatic veins, ovarian veins, suprahepatic veins, and mesenteric veins 3–6 …”

Section: Introductionmentioning

confidence: 99%

“…2 Variants of Lemierre's syndrome caused by Fusobacterium species have also been described in multiple anatomic locations such as hepatic veins, ovarian veins, suprahepatic veins, and mesenteric veins. [3][4][5][6] Mesenteric vein thrombosis (MVT) is a rare condition that accounts for one in 5000 to 15,000 hospital admissions and one in 1000 admissions to the emergency department, with high mortality (19%-23%). 7 Primary or idiopathic MVT accounts for 21%-49% of the cases and the proportion of patients with idiopathic cases decreases with more extensive evaluation.…”

Section: Introductionmentioning

confidence: 99%

Fusobacterium bacteremia presenting with inferior mesenteric vein thrombosis

Sapkota

Shrestha

Sharma³

et al. 2023

Clinical Case Reports

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Case Report: Abdominal variant of Lemierre’s syndrome

Pollard

Patel

et al. 2023

F1000Res

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Lemierre's syndrome is a rare condition characterized by Fusobacterium bacteremia from an oropharyngeal source with septic emboli causing internal jugular vein (IVJ) thrombophlebitis in an otherwise young and healthy host. Rare variants of this rare disease have been described impacting the gastrointestinal, pulmonary, neurologic, musculoskeletal, soft tissue, and genitourinary systems. We discuss a case of an abdominal variant of Lemierre's syndrome. An otherwise young and healthy male presented with two pyogenic hepatic abscesses, Fusobacterium necrophorum bacteremia, and local hepatic venous thrombosis. The hepatic abscesses were percutaneously drained, he received broad-spectrum antibiotics and therapeutic-level anticoagulation, and he showed marked clinical improvement over a six-day hospital course. He was discharged with four weeks of daily oral and intravenous (IV) antibiotics, six months of direct oral anticoagulation, and close follow up. Clinicians should consider thrombophlebitis in more anatomical locations than the IVJ which is found classically in Lemierre’s syndrome in the setting of Fusobacterium bacteremia.

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Abdominal Lemierre Syndrome – An Odd Presentation of a Rare Entity

Cited by 3 publications

References 4 publications

Abdominal variant of Lemierre’s Syndrome in a Patient with Pancreatic Adenocarcinoma

Abdominal variant of Lemierre’s Syndrome in a Patient with Pancreatic Adenocarcinoma

Fusobacterium bacteremia presenting with inferior mesenteric vein thrombosis

Case Report: Abdominal variant of Lemierre’s syndrome

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