Abdominal CT findings may suggest coeliac disease

Tomei, Ernesto; Diacinti, Daniele; Marini, Mario; Mastropasqua, M; Tola, Marco Di; Sabbatella, L.; Picarelli, Antonio

doi:10.1016/j.dld.2004.10.016

Cited by 50 publications

(38 citation statements)

References 24 publications

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“…If an overt lymphoma is suspected, an extensive work-up is required including gastroscopy with multiple duodenal biopsies, CT chest, abdomen and pelvis. 74 Other potentially useful investigations include CT or MR enteroclysis, 153 PET scanning, 154 video capsule enteroscopy and double balloon enteroscopy. 74,155 In some cases, laparotomy, intraoperative enteroscopy and full thickness biopsies are necessary.…”

Section: 146mentioning

confidence: 99%

Systematic review: the evidence base for long‐term management of coeliac disease

Haines

Anderson

Gibson

2008

Aliment Pharmacol Ther

182

144

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Section: 146mentioning

confidence: 99%

Systematic review: the evidence base for long‐term management of coeliac disease

Haines

Anderson

Gibson

2008

Aliment Pharmacol Ther

182

144

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“…More than 80% of the cases can be detected prenatally or in the first two years of life, but this rare entity may remain asymptomatic for years, even until adulthood, unless complications occur (2). Many complications related to colonic duplications have been reported in adults, such as obstruction, bleeding, intussusception, or melena (3)(4)(5)(6). Peritonitis related to perforation of the duplication is a rare condition in adults (1,3).…”

Section: To the Editormentioning

confidence: 99%

“…Chronic exposure to antigens passing through the small intestine with impaired permeability and a specific reaction of the wall of the small intestine against chronic inflammation have been suggested as possible causes (4,5). In a trial conducted by Tomei et al (6) that evaluated abdominal CT findings of celiac disease, ascites was found in 2 of 28 patients (7.1%) and mesenteric LAP was determined in 12 patients (42.8%), and in 2 of these 12 patients, lymph node cavitation was observed. In another trial, which evaluated the role of magnetic resonance imaging (MRI) in celiac disease, mesenteric LAP was determined in 41.9% and ascites was found in 6.5% of cases (7).…”

mentioning

confidence: 99%

A rare manifestation of celiac disease: Mesenteric lymphadenopathy with cavitation

Ustaoğlu¹,

Bektaş²,

Bakir³

et al. 2012

Turk J Gastroenterol

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“…In optimally distended loops, the small bowel wall is usually <3-4 mm thick. With CT enterography, Tomei et al [19] found this feature in 21% of patients with CD, the mean thickness being 9 mm (range 5-18). In a study on CT enteroclysis that included 44 patients with CD and 44 control subjects, the sensitivity and specificity of diffuse jejunal wall thickening were 0.66 and 0.98 [12].…”

Section: Radiology In Uncomplicated CDmentioning

confidence: 99%

Small Bowel Imaging in Celiac Disease

Weyenberg

Mulder²,

Waesberghe

2015

Dig Dis

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Background: Modern small bowel imaging techniques allow detailed depiction of small-intestinal abnormalities. The role of these techniques in the investigation of celiac disease is increasing, especially in patients with suspected complicated celiac disease. Key Messages: In general, there is no need for radiological small bowel imaging in uncomplicated celiac disease. It is however important that clinicians and radiologists are aware of certain specific radiological findings that may suggest celiac disease, especially since celiac disease is often not considered in adult patients, and small bowel radiology may be performed before specific tests for celiac disease. Radiological abnormalities can be observed with both conventional small bowel radiology studies, like small bowel follow-through or double-contrast small bowel enteroclysis, and newer modalities, like computed tomography or magnetic resonance enterography or enteroclysis. These signs include a decreased number of jejunal folds, an increased number of ileal folds, small bowel dilatation, wall thickening and intussusception. Extraintestinal abnormalities include mesenteric lymphadenopathy, vascular changes and splenic atrophy. Abnormalities congruent with refractory celiac disease type II include a severe decrease in jejunal folds, infiltration of the mesenteric fat and thickening of the small bowel wall. Additionally, a severely decreased splenic volume may indicate complicated celiac disease. Malignant complications of celiac disease, such as enteropathy-associated T-cell lymphoma and small-intestinal adenocarcinoma, can be reliably investigated with cross-sectional enteroclysis techniques. Conclusions: Small bowel imaging and especially cross-sectional enteroclysis techniques are important extensions to the diagnostic workup of clinicians involved in the care of patients with celiac disease, especially those with suspected complicated disease.

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Abdominal CT findings may suggest coeliac disease

Cited by 50 publications

References 24 publications

Systematic review: the evidence base for long‐term management of coeliac disease

Systematic review: the evidence base for long‐term management of coeliac disease

A rare manifestation of celiac disease: Mesenteric lymphadenopathy with cavitation

Small Bowel Imaging in Celiac Disease

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