Abdominal aortic calcification in predialysis patients: Contribution of traditional and uremia‑related risk factors

Timofte, Delia; Dragoș, Dorin; Balcangiu‐Stroescu, Andra-Elena; Tănăsescu, Maria‐Daniela; Bălan, Daniela Gabriela; Răducu, Laura; Tulin, Adrian; Ştiru, Ovidiu; Ionescu, Dorin

doi:10.3892/etm.2020.8607

Cited by 10 publications

(10 citation statements)

References 40 publications

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“…Studies have emphasized the strong correlation between valvular and VC and bone diseases in the hemodialysis patients ( 88 ) and also the high incidence of VC since the predialytic stages of CKD is strongly correlated with age, cardiovascular comorbidities, osteoporosis and decrease of GFR ( 91 ).…”

Section: Calcium (Ca 2+ )mentioning

confidence: 99%

Dyselectrolytemia‑management and implications in hemodialysis (Review)

et al. 2020

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Hemodialysis is a method for the renal replacement therapy followed by series of acute and chronic complications. Dyselectrolytemia appears in patients undergoing dialysis through mechanisms related to the chronic kidney disease and/or to the dialysis therapy and for this group of patients it is associated with an increase of morbidity and mortality. The dialysate has a standard composition, which can be modified according to the patient's characteristics. During hemodialysis patients are exposed to 18,000-36.000 litres of water/year, and the water purity along with the biochemical composition of the dialysate are essential. The individualization of the dialysis prescription is recommended for each patient and it has an important role in preventing the occurrence of dyselectrolyemia. The individualization of the treatment prescription according to the blood constants of each patient is the prerogative of the nephrologist and the association of the electrolyte imbalances with the patients cardiovascular mortality explains the importance of paying special attention to them.

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Section: Calcium (Ca 2+ )mentioning

confidence: 99%

Dyselectrolytemia‑management and implications in hemodialysis (Review)

et al. 2020

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“…Research has shown that exposure to low-calcium dialysate (<2.5 mEq/l) is associated with an increase in the risk of SCD by 40% (189). On the other hand, other studies have shown that the use of high-calcium dialysate is correlated with an increase in mortality, by acceleration of the vascular calcification and by increasing the myocardium vulnerability to arrhythmias (190)(191)(192).…”

Section: Managementmentioning

confidence: 99%

Management of acute intradialytic cardiovascular complications: Updated overview (Review)

et al. 2021

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An increasing number of patients require renal replacement therapy through dialysis and renal transplantation. Chronic kidney disease (CKD) affects a large percentage of the world's population and has evolved into a major public health concern. Diabetes mellitus, high blood pressure and a family history of kidney failure are all major risk factors for CKD. Patients in advanced stages of CKD have varying degrees of cardiovascular damage. Comorbidities of these patients, include, on the one hand, hypertension, hyperlipidemia, hyperglycemia, hyperuricemia and, on the other hand, the presence of mineral-bone disorders associated with CKD and chronic inflammation, which contribute to cardiovascular involvement. Acute complications occur quite frequently during dialysis. Among these, the most important are cardiovascular complications, which influence the morbidity and mortality rates of this group of patients. Chronic hemodialysis patients manifest acute cardiovascular complications such as intradialytic hypotension, intradialytic hypertension, arrhythmias, acute coronary syndromes and sudden death. Thus, proper management is extremely important.

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“…A large proportion of patients suffering from CKD also have mineral and bone disorders and vascular calcifications which, by increasing the arterial stiffness, trigger HBP. These vascular changes are more intense in the chronic hemodialyzed patients ( 41 , 42 ). A high level of uric acid is associated with the increase of blood pressure and it is an important risk factor for cardiovascular diseases ( 43 ).…”

Section: Renal Aging-clinical Significance and Patient Managementmentioning

confidence: 99%

Kidney aging process and the management of the elderly patient with renal impairment (Review)

et al. 2021

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As life expectancy increases, a rise in the number of chronically ill patients is observed due to the aging population. Among the various diseases, chronic kidney disease is at present one of the main causes of morbidity and, due to its typical complications, it is also one of the most important causes of mortality in the general population. For these reasons, the understanding of the kidney aging process, its consequences and its adequate management are essential. The judicious use of certain types of drugs, the prevention of episodes of renal injury either by toxic mechanisms or by dehydration are important aspects and are part of the apropriate approach for elderly patients. The most effective treatment of various types of conditions with a negative impact on renal function and for which an increased incidence is known as we age should also be considered. Thus, in the case of elderly patients, in order to protect the kidneys, an integrative approach is recommended, one that includes both elements of prevention and the appropriate treatment of existing diseases.

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Abdominal aortic calcification in predialysis patients: Contribution of traditional and uremia‑related risk factors

Cited by 10 publications

References 40 publications

Dyselectrolytemia‑management and implications in hemodialysis (Review)

Dyselectrolytemia‑management and implications in hemodialysis (Review)

Management of acute intradialytic cardiovascular complications: Updated overview (Review)

Kidney aging process and the management of the elderly patient with renal impairment (Review)

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