Abdominal Aortic Aneurysm Screening Reduces Mortality: Meta-analyses of Randomized, Controlled Trials

A further meta-analysis of population-based screening for abdominal aortic aneurysm

“…3 Lederle 3 and Koelemay, 4 however, revealed errors in the meta-analysis 2 and claimed that the reduction in all-cause mortality failed to reach statistical significance. Furthermore, Lederle 3 indicated that previous meta-analyses, including ours, 1,2,[5][6][7][8] with the exception of a systematic review by Fleming et al 9 for the US Preventive Services Task Force (USPSTF), had made the same error of using age unadjusted deaths from one of the randomized controlled trials (Western Australia study 10 ). In 2009, Thompson et al 11 presented new information from the 10-year follow-up in another randomized controlled trial (Multicentre Aneurysm Screening Study [MASS]).…”