Biomater. Sci.
 2024
DOI: 10.1039/d3bm01674a
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ABCD of IA: A multi-scale agent-based model of T cell activation in inflammatory arthritis

David A. McBride,
James S. Wang,
Wade T. Johnson
et al.

Abstract: The study develops a computational framework to model factors that lead to the evolution of autoreactive T cells in inflammatory arthritis. The results provide a tool for planning immunomodulatory strategies focused on new disease-modifying agents.

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