Abandonment of treatment for childhood cancer: position statement of a SIOP PODC Working Group

Mostert, Saskia; Arora, Ramandeep Singh; Arreola, Magda; Bagai, Poonam; Friedrich, Paola; Gupta, Sumit; Kaur, Gurvinder; Koodiyedath, Bindu; Kulkarni, Ketan; Lam, Catherine G.; Luna‐Fineman, Sandra; Pizer, Barry; Rivas, Silvia; Rossell, Nuria; Sitaresmi, Mei Neni; Tsimicalis, Argerie; Weaver, Meaghann S.; Ribeiro, Raul C.

doi:10.1016/s1470-2045(11)70128-0

Cited by 207 publications

(245 citation statements)

References 7 publications

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“…Failure to complete treatment is the most common cause of treatment failure for children with cancer in low-income countries [5,33]. There are many reasons.…”

Section: Social Support To Prevent Failure To Complete Treatmentmentioning

confidence: 99%

SIOP PODC: Clinical guidelines for the management of children with Wilms tumour in a low income setting

Israëls

Moreira

Scanlan

et al. 2012

Pediatric Blood & Cancer

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Wilms tumour is a relatively common and curable paediatric tumour. Known challenges to cure in low income countries are late presentation with advanced disease, malnutrition, failure to complete treatment and limited facilities. In this article, management recommendations are given for a low income setting where only the minimal requirements for treatment with curative intent are available (setting 1). These include general management, supportive care, social support and registration of patients. Recommendations specific for Wilms tumour care include diagnostic procedures with emphasis on the role of ultrasonography, preoperative chemotherapy with a reduced dosage for malnourished children and postoperative chemotherapy based on surgical staging. Pediatr Blood Cancer 2013; 60: 5–11. © 2012 Wiley Periodicals, Inc.

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“…Failure to complete treatment is the most common cause of treatment failure for children with cancer in low-income countries [5,33]. There are many reasons.…”

Section: Social Support To Prevent Failure To Complete Treatmentmentioning

confidence: 99%

SIOP PODC: Clinical guidelines for the management of children with Wilms tumour in a low income setting

Israëls

Moreira

Scanlan

et al. 2012

Pediatric Blood & Cancer

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“…[5] In some LIC, children comprise 40-50% of the population, and the proportion of childhood cancers represents 3-10% of cancer cases, [8] whereas in HIC, this proportion is only about 1%. [8] Mortality patterns also differ since cancer accounts for 4-5% of childhood deaths in HIC (where cancer is the leading cause of death from disease among children aged [1][2][3][4][5][6][7][8][9][10][11][12][13][14], and less than 1% in LMIC (where deaths from infectious diseases are more prominent). [5] In this article, we summarize the recent progress of the Paediatric Oncology in Developing Countries (PODC) committee of the International Society of Paediatric Oncology (SIOP) to address the disparities in treatment and outcomes of childhood cancer in LMIC.…”

Section: Children With Cancer In Low-and Middle-income Countriesmentioning

confidence: 99%

Improving Care for Children With Cancer in Low- and Middle-Income Countries-A SIOP PODC Initiative

Arora

Challinor

Howard

et al. 2015

Pediatr Blood Cancer

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The Paediatric Oncology in Developing Countries (PODC) committee of International Society of Paediatric Oncology (SIOP) has 10 working groups that provide a forum for individuals to engage, network, and implement improvements in the care of children with cancer in low-and middle-income countries. The development of adapted guidelines (medulloblastoma, retinoblastoma, Wilms tumor, neuroblastoma, retinoblastoma, Burkitt lymphoma, supportive care), advocacy and awareness (on hospital detention and essential drugs), education and training, and global mapping (nutritional practice, abandonment rates, and twinning collaborations) have been the initial areas of focus, and the impact of some of these activities is evident, for example, in the SIOP Africa PODC Collaborative Wilms tumor project.

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Asian Pac J Cancer Prev, 15 (8), 3593-3599

IntroductionChildhood cancer survival is lower in low-income countries (<35%) than in high-income countries (80%) (Mostert et al, 2011;Rohani-Rasaf et al, 2012). Several factors contribute to this discrepancy: death from toxicity, relapse and non-adherence.

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mentioning

confidence: 99%

Parents' and Health-Care Providers' Perspectives on Side-Effects of Childhood Cancer Treatment in Indonesia

Gunawan¹,

Wolters²,

Dongen³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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Asian Pac J Cancer Prev, 15 (8), 3593-3599 IntroductionChildhood cancer survival is lower in low-income countries (<35%) than in high-income countries (80%) (Mostert et al., 2011;Rohani-Rasaf et al., 2012). Several factors contribute to this discrepancy: death from toxicity, relapse and non-adherence. Treatment abandonment, a severe form of non-adherence and seldom seen in high-income countries, is the most prominent factor. Recently, various studies indicated that nonadherence and abandonment are not merely caused by socio-economic hardships, but also by psychological aspects and side-effects of chemotherapy (Yeh et al., 1999;De Oliveira et al., 2005;Bonilla et al., 2009;Sitaresmi et al., 2010;Wang et al., 2011).Chemotherapy-related side-effects may deteriorate the child's quality of life and hinder families' acceptance and adherence with prescribed medication (Yeh et al.,1999;

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Abandonment of treatment for childhood cancer: position statement of a SIOP PODC Working Group

Cited by 207 publications

References 7 publications

SIOP PODC: Clinical guidelines for the management of children with Wilms tumour in a low income setting

SIOP PODC: Clinical guidelines for the management of children with Wilms tumour in a low income setting

Improving Care for Children With Cancer in Low- and Middle-Income Countries-A SIOP PODC Initiative

Parents' and Health-Care Providers' Perspectives on Side-Effects of Childhood Cancer Treatment in Indonesia

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